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ИЗУЧЕНИЕ ЭФФЕКТИВНОСТИ ДЕЙСТВИЯ НОВОГО ОТЕЧЕСТВЕННОГО БЕЛКОВО-СОЛЕВОГО КРОВЕЗАМЕНИТЕЛЯ ПРИ ПЕРИТОНИТЕ

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Биомедицина ва амалиёт журнали

Биомедицина ва амалиёт журнали

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АННОТАЦИЯ СТАТЬИ

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A new original domestic multifunctional blood substitute «Yantaroprotein» was developed at the Scientific Research Institute of Hematology and Blood Transfusion of the Ministry of Health of the Republic of Uzbekistan. «Yantaroprotein» – providing immunomodulating, gemostimulating, antiinflammatory, antitumor and antioxidant effect, which has the ability to restore metabolic processes at the cellular and tissue levels in critical conditions. Research objective – The experiments were performed on a model of experimental peritonitis on 90 rats weighing 180 ± 250 grams. The indices of endogenous intoxication, the state of LPO and AOS of blood were studied. This work presents the results of a study of the new blood substitute in peritonitis. Studied parameters of endogenous intoxication state of lipid peroxidation (LPO) and antioxidant levels. A new blood substitute preparation for infusions of «Yantaroprotein» of local production leads to normalization of endogenous intoxication, LPO and AOS recovery, more effective than the drug «Lactoprotein» used in medical practice, which allows it to be recommended in the complex treatment of peritonitis.

АВТОРЫ

T.Alimov

H.Karimov

SH.Aliyev

L.Shevchenko

Теги

# эндоген интоксикация# endogenous intoxication# «Янтаропротеин»# экспериментальный перитонит# эндогенная интоксикация# перекисное окисление липидов (ПО# антиоксидантная система (АОС).# “Янтаропротеин”# экспериментал перитонит# липидларни пероксид оксидланиши# антиоксидант тизимини (АОТ)# «Yantaroprotein»# lipid peroxidation (LPO)# antioxidant system (AOS)

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ROI:

https://eroi.uz/11.0037/A1119-0138

DOI:

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Список литературы

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