SYNTHESIS OF SCHIFF BASE BASED ON AMINOPOLYSACCHARIDES A CHITOSAN APIS MELLIFERA WITH SALICYLIC AND GLUTARALDEHYDES

1. Chitosan/edited by K.G. Skryabina, S.N. Mikhailova, V.P.Varlamova – Moscow: Center “Bioengineering” RAS, 2013. – 593 p. 2. Ikhtiyarova G.A. Preparation, properties and application of biodegradable polymers of chitin and chitosan / Monograph. Standard polygraph. -2017. P.96. 3. Vikhoreva G.A., Shablykova E.A., Kildeeva N.R. Modification of chitosan films with glutaraldehyde to regulate their solubility and swelling // Khim. fibers. 2001. No. 3. p. 38-42.

4. Monteiro, OAC Jr. Some studies of crosslinking chitosan-glutaraldehyde interaction in a homogeneous system / OAC Monteiro Jr., C. Airoldi // International Journal of Biological Macromolecules. 1999. Vol. 26. – P. 119–128. 5. Fen, YW Optical Properties of Crosslinked Chitosan Thin Film with Glutaraldehyde Using Surface Plasmon Resonance Technique / YW Fen, WMM Yunus, MM Moksin, ZA Talib, NA Yusof // American J. of Engineering and Applied Sciences. – 2011. – Vol. 4, No. 1. – R. 61-65. 6. Ramachandran, S. Formulation and Characterization of Glutaraldehyde Cross-Linked Chitosan Biodegradable Microspheres Loaded with Famotidine / S. Ramachandran, S. Nandhakumar, MD Dhanaraju // Tropical Journal of Pharmaceutical Research. – 2011. Vol. 10, No. 3. – R. 309-316.

7. Singh, B. Chemical modification of chitosan with pH-sensitive molecules and specific ligands for efficient DNA transfection and RNA silencing // Journal of nanoscience and nanotechnology. – 2014. – T. 14. No. 1. – S. 564-576. 8. Jiao, T. F. Synthesis and Characterization of Chitosan-based Schiff Base Compounds with Aromatic Substituent Groups / T. F. Jiao [et al.] i / Iranian Polymer Journal. – 2011. Vol. 20, No. 2. – R. 123-136. 9. Dua, Y. Preparation of Modified Chitosan By Salicylaldehyde / Y. Dua [et al.] // International Conference on Electronic & Mechanical Engineering and Information Technology. – 2011. – R. 2908-2911.

10. Jiao, T. F. Synthesis and Characterization of Chitosan-based Schiff Base Compounds with Aromatic Substituent Groups / T. F. Jiao [et al.] / Iranian Polymer Journal. – 2011. – Vol. 20, No. 2. – R. 123-136. 11. Guinesi, LS Influence of some reactional parameters on the substitution degree of biopolymeric Schiff bases prepared from chitosan and salicylaldehyde / LS Guinesi, ETG Cavalheiro // Carbohydrate Polymers. 2006. – Vol. 65. – P. 557–561.

12. Jones P., Sandorfi K. Application of spectroscopy in chemistry. M. Foreign publishing house. lit., 1959. - 209 s. 13. P.E. Ignatieva, E.S. Zhavoronok O.A. Legonkova, S.A. Kedik Compositions based on aqueous solutions of chitosan and glutar aldehyde for embolization of blood vessels. Тонкие химические технологии / Fine Chemical Technologies. 2019 v.14 №1. 14. Mengliev A.S., Ikhtiyarova G.A. Preparation of azomethine derivatives (schif bases) chitosan apis mellifera/ Technical science and innovation. No. 4/2022 y.pp.24-29.

15. Ikhtiyarova G.A., Mengliev A.S., Ulashev Sh.M. Selection of chitosan by cryogenic method from bee deaths and synthesis of schiff base based on salicyaldehyde and its use in fabric dying. Scientific journal “Oil and Gas”.publications of KKSNVO MNVO of the Republic of Kazakhstan . 16. Ulashev Sh., Ikhtiyarova G.A. Study of the interaction of the aminopolysaccharide chitosan Apis mellifera with glutaraldehyde // Composite Materials. – 2024. – No. 1. (in Rus)

1. Chitosan/edited by K.G. Skryabina, S.N. Mikhailova, V.P.Varlamova – Moscow: Center “Bioengineering” RAS, 2013. – 593 p. 2. Ikhtiyarova G.A. Preparation, properties and application of biodegradable polymers of chitin and chitosan / Monograph. Standard polygraph. -2017. P.96. 3. Vikhoreva G.A., Shablykova E.A., Kildeeva N.R. Modification of chitosan films with glutaraldehyde to regulate their solubility and swelling // Khim. fibers. 2001. No. 3. p. 38-42.

4. Monteiro, OAC Jr. Some studies of crosslinking chitosan-glutaraldehyde interaction in a homogeneous system / OAC Monteiro Jr., C. Airoldi // International Journal of Biological Macromolecules. 1999. Vol. 26. – P. 119–128. 5. Fen, YW Optical Properties of Crosslinked Chitosan Thin Film with Glutaraldehyde Using Surface Plasmon Resonance Technique / YW Fen, WMM Yunus, MM Moksin, ZA Talib, NA Yusof // American J. of Engineering and Applied Sciences. – 2011. – Vol. 4, No. 1. – R. 61-65. 6. Ramachandran, S. Formulation and Characterization of Glutaraldehyde Cross-Linked Chitosan Biodegradable Microspheres Loaded with Famotidine / S. Ramachandran, S. Nandhakumar, MD Dhanaraju // Tropical Journal of Pharmaceutical Research. – 2011. Vol. 10, No. 3. – R. 309-316.

7. Singh, B. Chemical modification of chitosan with pH-sensitive molecules and specific ligands for efficient DNA transfection and RNA silencing // Journal of nanoscience and nanotechnology. – 2014. – T. 14. No. 1. – S. 564-576. 8. Jiao, T. F. Synthesis and Characterization of Chitosan-based Schiff Base Compounds with Aromatic Substituent Groups / T. F. Jiao [et al.] i / Iranian Polymer Journal. – 2011. Vol. 20, No. 2. – R. 123-136. 9. Dua, Y. Preparation of Modified Chitosan By Salicylaldehyde / Y. Dua [et al.] // International Conference on Electronic & Mechanical Engineering and Information Technology. – 2011. – R. 2908-2911.

10. Jiao, T. F. Synthesis and Characterization of Chitosan-based Schiff Base Compounds with Aromatic Substituent Groups / T. F. Jiao [et al.] / Iranian Polymer Journal. – 2011. – Vol. 20, No. 2. – R. 123-136. 11. Guinesi, LS Influence of some reactional parameters on the substitution degree of biopolymeric Schiff bases prepared from chitosan and salicylaldehyde / LS Guinesi, ETG Cavalheiro // Carbohydrate Polymers. 2006. – Vol. 65. – P. 557–561.

12. Jones P., Sandorfi K. Application of spectroscopy in chemistry. M. Foreign publishing house. lit., 1959. - 209 s. 13. P.E. Ignatieva, E.S. Zhavoronok O.A. Legonkova, S.A. Kedik Compositions based on aqueous solutions of chitosan and glutar aldehyde for embolization of blood vessels. Тонкие химические технологии / Fine Chemical Technologies. 2019 v.14 №1. 14. Mengliev A.S., Ikhtiyarova G.A. Preparation of azomethine derivatives (schif bases) chitosan apis mellifera/ Technical science and innovation. No. 4/2022 y.pp.24-29.

15. Ikhtiyarova G.A., Mengliev A.S., Ulashev Sh.M. Selection of chitosan by cryogenic method from bee deaths and synthesis of schiff base based on salicyaldehyde and its use in fabric dying. Scientific journal “Oil and Gas”.publications of KKSNVO MNVO of the Republic of Kazakhstan . 16. Ulashev Sh., Ikhtiyarova G.A. Study of the interaction of the aminopolysaccharide chitosan Apis mellifera with glutaraldehyde // Composite Materials. – 2024. – No. 1. (in Rus)