As we know, on March 11, 2020, the World Health Organization declared a pandemic of SARS-CoV-2 (COVID-19) coronavirus, and from that day, a new coronavirus pandemic started in all countries. It is a new type of disease whose development, course, clinic and treatment are not yet fully understood, making it difficult to controlthe disease. A total of 54,482,449 cases and 1,318,612 deaths have been diagnosed, according to data released Nov. 16 by Johnson Hopkins University in the United States. Pregnant women account for 2-5% of cases and the mortality rate is as high as 25% (SSV Russia, May 2020). The highest risk group of pregnant women with COVID-19 billion are additional somatic diseases: cardiovascular diseases, arterial hypertension, chronic lung diseases, bronchial asthma of moderate and severe degree, diabetes mellitus, cancer, obesity (TVI>40), kidney disease, liver disease, AFS. This review explores the modes of action and resistance mechanisms of widely used antimicrobials, as well as the current state of AMR in the most critical resistant bacteria identified by theWHO’s global priority pathogens list.In this review, the complications that occur in women who have had covid 19 in the 2nd trimester of pregnancy and the specific specifics of childbirth are studied.