Under the conditions of low saline, moderate and saline soils of the Andijаn region, the local UzDEF and FanDEF defoliants have been identified to have their impact on the opening and closing of the cotton leaf. In this case Liquid XMD in norms 5,0-6,0-7,0 liters hectare compared to 8,0 liters in low saline area at 6,0-7,0 liters, moderate salinity – 5,0-6,0 liters compared with 7,0 liters of deforesters in the un-saline area.