The article explores the application of Kathryn Sorrells' Intercultural Praxis Model (IPM) within Central Asian settings, notably Uzbekistan. Because the global arena is becoming more interconnected as a result of globalization, successful intercultural communication becomes ever more important, especially in multicultural-rich settings like Central Asia. The study explores how the six interconnected elements of the IPM, Inquiry, Framing, Positioning, Dialogue, Reflection, and Action, can be practically applied in navigating complex intercultural communication in Uzbekistan's multicultural social space.Drawing on Central Asia's ancient heritage as a meetingpoint of civilizations along the old Silk Road, the article shows how classical cultural norms, contemporary influences, and Soviet legacies blend together to create unique intercultural dynamics. Through practical examples of Uzbek practices of hospitality, gender relations, business negotiations, and educational exchange, the research demonstrates the way each element of the IPM can lead to intercultural competence and mutual understanding.The study illustrates that successful intercultural communication in Central Asia requires more than knowledge of cultures, it requires critical self-consciousness, awareness of power relations, and commitment to socially responsible action. The article concludes that through systematic application of the IPM model, both individual and institutional stakeholders can convert intercultural challenges into opportunities for effective communication, towards social cohesion and sustainable development in Central Asia's multicultural societies