Central Asia is one of the most developed area in science and culture since ancient times. It is characterized by the region's favorable geographical climate, location on the Great Silk Road and crossroads of cultures, as well as rich scientific and practical experience and skills that are the result of the hard and selfless work of the people of the region. Admittedly, the historical services of Uzbekistan, which is a strategic center of the region, are invaluable. Because the ancient historical cities, which are the main ancient scientific and cultural centers in Central Asia, are located on the territory of Uzbekistan. These historical centers have produced a lot encyclopedic scholars to the world. In Central Asia, especially in Uzbekistan, the fields of astronomy, mathematics, medicine, chemistry, textiles, architecture, cultural studies, philosophy, music, linguistics and literature were well developed. The reason is that the history of science in the region dates back to very ancient times, it has deep roots. Archaeological excavations and research in Central Asia, particularly in Uzbekistan, have shown that people lived on this land from time immemorial, and the first empirical knowledge began to form in them, and thus gradually began to form buds of thought, which were combined to create written monuments (eg Avesto and b.). The foundations of astronomy, mathematics, medicine, architecture emerged.