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5-HMF SINTEZI SHARHI: KATALIZ VA TEXNOLOGIYALAR

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5-Gidroksimetilfurfurol (5-GMF) bioyoqilg‘ilar (2,5-dimetilfuran, 5-etoksimetilfurfuril efir), biopolimerlar (2,5-furankarbon kislota) va farmatsevtik oraliq mahsulotlar ishlab chiqarish uchun prekursor sifatida xizmat qiladigan bioiqtisodiyotda asosiy platforma molekulasi sifatida tan olingan. Ushbu sharhda turli murakkablikdagi uglevod xom ashyosidan - monosaxaridlardan (fruktoza, glyukoza) sellyuloza va lignotsellyuloza biomassasigacha (sholi somoni) 5-GMF sinteziga zamonaviy yondashuvlar tizimlashtirilgan. Katalitik tizimlar (gomogen kislotalar, ionli suyuqliklar, geterogen katalizatorlar, shu jumladan funksionallashgan silikagel SiO2-Imi-SO3H va sulfatlangan seolit HSO3-ZSM-5), erituvchilar ta’siri (dimetilsulfoksid, ikki fazali suv/organik erituvchilar tizimlari, shu jumladan dixlormetan/tetragidrofuran), jarayonlarni jadallashtirish usullari (ultratovush, mikroto‘lqinlar) va qo‘shimcha reaksiyalarni bostirish strategiyalari batafsil tahlil qilingan. 5-GMF ni kimyoviy o‘zgartirishning asosiy yo‘llari, ishlab chiqarishning texnik-iqtisodiy va ekologik jihatlari hayotiy siklni baholash (TSB) va bibliometrik tahlil asosida muhokama qilinadi. Asosiy muammolar (katalizator va ajratish xarajatlari, barqarorlik) va istiqbolli tadqiqot yo‘nalishlari (arzon bifunksional katalizatorlar, chuqur evtektik erituvchilar, jarayon integratsiyasi, elektrokimyoviy usullar, nooziq-ovqat biomassasidan foydalanish) aniqlangan.

MUALIFLAR

Teglar

# целлюлоза# cellulose# глюкоза# glucose# biomassa# biomass# биомасса# фруктоза# glyukoza# fructose# fruktoza# 5-hydroxymethylfurfural (5-HMF)# carbohydrate dehydration# ionic liquids# heterogeneous catalysts# biphasic systems# platform molecules# renewable feedstocks# biofuels# furandicarboxylic acid (FDCA)# 5-гидроксиметилфурфурол (5-ГМФ)# дегидратация углеводов# ионные жидкости# гетерогенные катализаторы# двухфазные системы# платформенные молекулы# биотопливо# фурандикарбоновая кислота (ФДКА)# 5-gidroksimetilfurfurol (5-GMF)# uglevodlar degidratatsiyasi# sellyuloza# ion suyuqliklar# geterogen katalizatorlar# ikki fazali tizimlar# platforma molekulalari# qayta tiklanadigan xomashyolar# bioyoqilg‘ilar# furankarbon kislotasi (FDKK)

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Foydalanilgan adabiyotlar

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[2] Wang, H., Zhu, C., Li, D., et al. (2019). Recent advances in catalytic conversion of biomass to 5-hydroxymethylfurfural and 2,5-dimethylfuran. Renewable and Sustainable Energy Reviews, 103, 227–247. https://doi.org/10.1016/j.rser.2018.12.010

[3] van Putten, R.-J., van der Waal, J. C., de Jong, E., et al. (2013). Hydroxymethylfurfural: A versatile platform chemical made from renewable resources. Chemical Reviews, 113(3), 1499–1597. https://doi.org/10.1021/cr300182k

[4] Zhang, Z., & Huber, G. W. (2018). Catalytic oxidation of carbohydrates into organic acids and furan chemicals. Chemical Society Reviews, 47(4), 1351–1390. https://doi.org/10.1039/C7CS00213K

[5] Dutta, S., De, S., & Saha, B. (2012). A brief summary of the synthesis of polyester building-block chemicals and biofuels from 5-hydroxymethylfurfural. ChemPlusChem, 77(4). https://doi.org/10.1002/cplu.201100035

[6] Thananatthanachon, T., & Rauchfuss, T. B. (2010). Efficient production of the liquid fuel 2,5-dimethylfuran from fructose using formic acid as a reagent. Angewandte Chemie International Edition, 49(37), 6616–6618. https://doi.org/10.1002/anie.201002267

[7] Dutta, S., Wu, L., & Mascal, M. (2015). Efficient, green, and scalable production of 5-ethoxymethylfurfural from fructose catalyzed by sulfuric acid. ChemSusChem, 8(10), 1711–1715. https://doi.org/10.1002/cssc.201403481

[8] Sajid, M., Zhao, X., & Liu, D. (2018). Production of 2,5-furandicarboxylic acid (FDCA) from 5-hydroxymethylfurfural (HMF): Recent progress focusing on chemical catalytic routes. Green Chemistry, 20(24), 5427–5453. https://doi.org/10.1039/C8GC02680G

[9] Kröger, M., Prüße, U., & Vorlop, K.-D. (2012). A new approach for the production of 2,5-furandicarboxylic acid by in situ oxidation of 5-hydroxymethylfurfural starting from fructose. Topics in Catalysis, 13(3), 237–242. https://doi.org/10.1023/A:1009017929727

[10] Davis, S. E., Houk, L. R., Tamargo, E. C., et al. (2011). Oxidation of 5-hydroxymethylfurfural over supported Pt, Pd, and Au catalysts. Catalysis Today, 160(1), 55–60. https://doi.org/10.1016/j.cattod.2010.06.004

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[1] Jiang, Z., Zeng, Y., Hu, D., et al. (2023). Chemical transformations of 5-hydroxymethylfurfural into highly added value products: Present and future. Green Chemistry, 25, 871–892. https://doi.org/10.1039/D2GC03444A

[2] Wang, H., Zhu, C., Li, D., et al. (2019). Recent advances in catalytic conversion of biomass to 5-hydroxymethylfurfural and 2,5-dimethylfuran. Renewable and Sustainable Energy Reviews, 103, 227–247. https://doi.org/10.1016/j.rser.2018.12.010

[3] van Putten, R.-J., van der Waal, J. C., de Jong, E., et al. (2013). Hydroxymethylfurfural: A versatile platform chemical made from renewable resources. Chemical Reviews, 113(3), 1499–1597. https://doi.org/10.1021/cr300182k

[4] Zhang, Z., & Huber, G. W. (2018). Catalytic oxidation of carbohydrates into organic acids and furan chemicals. Chemical Society Reviews, 47(4), 1351–1390. https://doi.org/10.1039/C7CS00213K

[5] Dutta, S., De, S., & Saha, B. (2012). A brief summary of the synthesis of polyester building-block chemicals and biofuels from 5-hydroxymethylfurfural. ChemPlusChem, 77(4). https://doi.org/10.1002/cplu.201100035

[6] Thananatthanachon, T., & Rauchfuss, T. B. (2010). Efficient production of the liquid fuel 2,5-dimethylfuran from fructose using formic acid as a reagent. Angewandte Chemie International Edition, 49(37), 6616–6618. https://doi.org/10.1002/anie.201002267

[7] Dutta, S., Wu, L., & Mascal, M. (2015). Efficient, green, and scalable production of 5-ethoxymethylfurfural from fructose catalyzed by sulfuric acid. ChemSusChem, 8(10), 1711–1715. https://doi.org/10.1002/cssc.201403481

[8] Sajid, M., Zhao, X., & Liu, D. (2018). Production of 2,5-furandicarboxylic acid (FDCA) from 5-hydroxymethylfurfural (HMF): Recent progress focusing on chemical catalytic routes. Green Chemistry, 20(24), 5427–5453. https://doi.org/10.1039/C8GC02680G

[9] Kröger, M., Prüße, U., & Vorlop, K.-D. (2012). A new approach for the production of 2,5-furandicarboxylic acid by in situ oxidation of 5-hydroxymethylfurfural starting from fructose. Topics in Catalysis, 13(3), 237–242. https://doi.org/10.1023/A:1009017929727

[10] Davis, S. E., Houk, L. R., Tamargo, E. C., et al. (2011). Oxidation of 5-hydroxymethylfurfural over supported Pt, Pd, and Au catalysts. Catalysis Today, 160(1), 55–60. https://doi.org/10.1016/j.cattod.2010.06.004

[11] Ромашов, Л. В. (2017). Исследование свойств 5-(гидроксиметил)фурфурола и его применение в синтезе биологически активных соединений и их аналогов (Канд. диссертация).

[12] Kuster, B. F. M. (1990). 5-Hydroxymethylfurfural (HMF): A review focusing on its manufacture. Starch – Stärke, 42(8), 314–321. https://doi.org/10.1002/star.19900420808

[13] Girisuta, B., Janssen, L. P. B. M., & Heeres, H. J. (2006). A kinetic study on the decomposition of 5-hydroxymethylfurfural into levulinic acid. Green Chemistry, 8(8), 701–709. https://doi.org/10.1039/B518176C

[14] Antal, M. J., Mok, W. S. L., & Richards, G. N. (1990). Mechanism of formation of 5-(hydroxymethyl)-2-furaldehyde from D-fructose and sucrose. Carbohydrate Research, 199(1), 91–109. https://doi.org/10.1016/0008-6215(90)84096-D

[15] Jung, D., Körner, P., & Kruse, A. (2021). Kinetic study on the impact of acidity and acid concentration on the formation of 5-hydroxymethylfurfural (HMF), humins, and levulinic acid in the hydrothermal conversion of fructose. Biomass and Bioenergy, 154, 106231. https://doi.org/10.1007/s13399-019-00507-0

[16] Sorokina, K. N., Taran, O. P., Medvedeva, T. B., & Parmon, V. N. (2017). Method for producing 5-hydroxymethylfurfural and ethanol from cellulose (Russian Patent RU2636004C1, November 17, 2017).

[17] Wanninayake, P., Rathnayake, M., Thushara, D., & Gunawardena, S. (2022). Conversion of rice straw into 5-hydroxymethylfurfural: Review and comparative process evaluation. Biomass Conversion and Biorefinery, 12, 1013–1047. https://doi.org/10.1007/s13399-021-01351-x

[18] Food and Agriculture Organization of the United Nations (FAO). (2022). Global assessment of biomass resources for 5-HMF production: Technical potential and sustainability.

[19] Dutta, S., De, S., Saha, B., et al. (2012). Advances in conversion of hemicellulosic biomass to furfural and upgrading to biofuels. Catalysis Science & Technology, 2(10), 2025–2036. https://doi.org/10.1039/C2CY20235B

[20] Avalon Industries AG. (2019). Method for the extraction of (5-hydroxymethylfurfural, 5-HMF) (European Patent EP3424914A1, January 9, 2019).

[21] Binder, J. B., & Raines, R. T. (2009). Simple chemical transformation of lignocellulosic biomass into furans for fuels and chemicals. Journal of the American Chemical Society, 131(5), 1979–1985. https://doi.org/10.1021/ja808537j

[22] Román-Leshkov, Y., Chheda, J. N., & Dumesic, J. A. (2006). Phase modifiers promote efficient production of hydroxymethylfurfural from fructose. Science, 312(5782), 1933–1937. https://doi.org/10.1126/science.1126337

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