logo
calendar19 Yanvar 2021
view26
Main language:Russian

О ВОЗМОЖНОСТИ НЕСОПРЯЖЁННЫХ МИТОХОНДРИЙ В БУРОМ ЖИРЕ НОВОРОЖДЕННЫХ МОРСКИХ СВИНОК

Field of Science:
pdf

600673113c76e.pdf

PDF

Scientific Bulletin of Namangan State University

Scientific Bulletin of Namangan State University

Publish Articlesee more

ARTICLE ANNOTATION

quote
the respiratory and phosphorylating activity of mitochondria of brown fat of guinea pigs during the oxidation of various substrates was studied. It was shown that pyruvate + malate is oxidized, is associated with the synthesis of ATP, but has high respiration V4; with succinate oxidation, a higher level of V4 is observed. The oxidation of NADH occurs in a completely non-conjugated way, since the oxidation process does not respond to the addition of ADP or uncoupling. The data obtained indicate the functioning of intensive non-conjugated respiration in the mitochondria of this tissue. It is able to convert respiration energy into heat, since the main function of brown fat is heat production.

AUTHORS

M.Mirzaolimov

A.Najimov

S.Mirzaev

A.Muxtorov

R.Akhmerov

B.Niyazmetov

A.Boymatov

E.Mirzaolimov

I.Qodirov

SH.Abdullayev

Tags

# mitochondria# митохондрия# две субпопуляции митохондрии# НАДН# АДФ# несопряженное дыхание# two subpopulations of mitochon# NADH# ADP# uncoupled respiration# mitoxondriya# mitoxondriyaning ikkita subpop# bog’lanmagan nafas olish

OTHER ARTICLES IN THIS JOURNAL

Rate Article

0
0 ratings
5
4
3
2
1

Article Identifiers

ROI:

https://eroi.uz/11.0031/A0121-0199

DOI:

Not Available

References

D. 2017. UCP1, the mitochondrial uncoupling protein of brown adipocyte: A personal contribution and a historical perspective. Biochimie, V. 134, P. 3-8.

Brand M.D., Paray J. I.,Ocloo A., Kokoszka J., Wallace D/ C., Brookes P.S.,& Cornwall E. J.. (2005). The basal conductance of mitochondria depends on adenine nucleotide translocase. Biochemical J., 392, 353-362

Jastroch M., Divakaruni A. S. , Mookerjee Sh. , Treberg J. R. , and . Brand M. D . 2010. Mitochondrial proton and electron leaks. Essays Biochem.; 47: 53–67.

Mitochondrial proton leak: a role for uncoupling proteins 2 and 3? Biochimica et Biophysica Acta (BBA) – Bioenergetics. V. 1504, 2001, P. 120–127.

Akhmerov R.N. Quantitate difference in mitochondria of endothermic and ectothermic animals. FEBS Letters (1986), 198 (2), 251-255.

Chance В., Williams G.S. Respiratory enzymes in oxidative phosphorylation // J. Biol. Chem. - 1955. - V. 217. – N.1. - P. 383-427.

Lowry O.H., Rosenbragh J., larr A.L., Randall R.J. Protein measurement with the folin phenol reagent. J.Biol, сhem. - 1951. - V. 193. - 1 1. - P. 265-275.

Ricquier D. and Bouillaud F.. (2000) The uncoupling protein homologues UCP1, UCP2, UCP3, Biochem. J. 345, 161-179,

Bouillaud F.. Couplan E., Pecqueur C. and Ricquier D. 2000. Homologues of the uncoupling protein from brown adipose tissue (UCP1): UCP2, UCP3, BMCP1, UCP4. Biochem . Biophys. Acta. 1504, 107-119

Klingenberg M., Winkler E. The reconstituted isolated uncoupling protein is a membrane potential driven H+ translocator.1985. MBO J.,V. 4 (12), pp. 3087-3092.

Akhmerov RN, Niyazmetov BA, Abdullaev GR. Different Views on the Tissue Thermogenesis of Organisms. Am. J. Biochem 8: 30-39, 2018.

Akhmerov R. N., Niyazmetov B. A. , Abdullayev G. R., On Novel Features of the Proton Leak and ossibility of Uncoupling Population of Mitochondria in Brown Adipose Tissue. American Journal of Biochemistry. 2018, 8(6): 107-113 DOI: 10.5923/j.ajb.20180806.01.