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QUANTITATIVE DETERMINATION OF LYOPHILIZED DRUG «KOBAFEN»

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ARTICLE ANNOTATION

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Lyophilization is widely used in the pharmaceutical industry, especially in the production of injectable dosage forms. The stability of the drug molecule is a key factor that affects the manufacturer's choice of the form of release of the drug-injectable drug in liquid or powder form. A new lyophilic preparation "KOBAFEN" was developed and the quantitative content of diclofenac sodium and vitamin B12 in the lyophilizate composition was determined for the preparation of a solution for injection using modern physical and chemical analysis methods.

AUTHORS

N.Abdullaeva

Ташкентский фармацевтический институт

R.Khusainova

Ташкентский фармацевтический институт

N.Yunusxojieva

Ташкентский фармацевтический институт

Tags

# ЮССХ# HPLC# ВЭЖХ# diclofenac sodium# «КОБАФЕН»# диклофенак натри# мекобаламин# лиофилизат# СФ# "KOBAFEN"# mecobalamin# lyophilisate# SF# диклофенак натрия

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References

1. "Фармацевтическая отрасль" №4 (63), август 2017 г.

2. Andersson H.C.and Shapira E. Biochemical and clinical response tohydroxocobalamin versus cyanocobalamin treatment in patients with methylmalonicacidemia and homocystinuria (cblC). Journal of Pediatrics 132, 121-124, 1998

3. Kuwabara S., Nakazawa R., Azuma N. et al. Intravenous methylcobalamin treatment for uremic and diabetic neuropathy in chronic hemodialysis patients. Internal Medicine, vol. 38, no. 6, pp. 472–475, 1999.

4. Хусаинова Р.А., Убайдуллаев Қ.А., Мухитдинова К.Ш., Жураева А.А. ВЭЖХ с применением УФ-и масс-спектрального детекторов в анализе цефалоспоринов // Фармацевтический вестник Узбекистана. -2019. - № 3.- С. 28-32.

5. European Pharmacopoeia (Eur.Ph.) 9.0 Edition