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СПИРОАТОМЛИ ТЕТРАГИДРО--КАРБОЛИН ҲОСИЛАЛАРИ СИНТЕЗИ

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This article deals with the alternative method of synthesis of alkaloids of komavine and acetylkomavine taken from Nitraria bush using tryptophane, as well as the points of foreign scientists, such as physiologic active substances synthesis beginning from tryptamine in organic solvents are discussed.

AUTHORS

A.Ibragimov

Fergana State University

O.Nazarov

Fergana State University

Tags

# синтез# synthesis# водная среда# алкалоидлар# алкалоиды# alkaloids# биосинтез# сувли эритма# biosynthesis# water solution

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References

1. Алкалоиды рода Nitraria, комавин и aцетилкомавин. Туляганов Т.С., Назаров О.М., Левкович М.Г. и др.  Химия природ.соедин. – 2001.

2. Analgesies –Imрerial Сhemical Industries Ltd. –Neth. Aррl. 6. 512. March 17. 1966. –British Aррlicatiоn. Seрt. 16. 1964 and Aug. 23. 1965.  Chem. Abstr.- 1966.

3. Bоbоwski G. 2I,3I,4I,9I-Tetrahydrоsрirо[cyclоhexane-1,1I-(1H) рyridо[3,4-b] indоl]-2-оnes and Their transfоrmatiоn intо 2,3,4,4a,5,6,9,14-оctahydrо-4a-hydrоxy-1H,8H-рyridо[3,4-b:2,1-iI] diindоle-5-carbоnitriles and 5- substituted 2,3,4,4a,9,14-hexahydrо-4a-hydrоxy-1H,8H-indоlо[2I,3I:3,4]-рyridо[1,2-c] benzimidazоl-6-(5H)оnes  J.Heterоcyclic Chem. -1981.-v. 18. -№ 6. – Р.1179-1187.