THE PHARMACOLOGICAL PROPERTIES OF A DRY EXTRACT OF CONVOLVULUS ARVENSIS L.

We studied locally irritant, allergic and cumulative properties of drug Konvaren derived from plant Convolvulus arvensis L. When applying 0.5-5% aqueous solution of the drug Konvaren surface of the skin erythema, swelling and redness were noted. When backfilling mucosal eyes of experimental animals a 10% aqueous solution of the drug is also not Konvaren mentioned side effects. When administered (gavage) of the drug in the first 1-5 days 50 mg / kg dose, 5-10 days 100 mg / kg, 11-15dni 500mg / kg and 16-20dni 1000 mg/kg were observed cumulative properties in organs and tissues. Furthermore, it has a sedative effect on the central nervous system and enhances the effect of narcotic and hypnotic.