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STUDY OF THE ACUTE TOXICITY OF HERB OF PHLOMIS THAPSOIDES, GROWN ON THE TERRITORY OF UZBEKISTAN

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ARTICLE ANNOTATION

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The acute toxicity of the herb of Phlomis thapsoides, grown on the territory of Uzbekistan, was studied. Acute toxicity studies were conducted according to a conventional method on white mongrel mice (both sexes). From the herb was prepared infusion, which was administered orally, at fve dose levels. As a result, it was found that the infusion of Phlomis thapsoides herbs is highly harmless, since LD50> 6000 mg / kg - the preparation belongs to the ffth toxicity class (almost non-toxic). The presence in the infusion of potential sedative and neurotropic activity was also established.

AUTHORS

M.Mullajonova

G.Orifjonova

B.Imamaliyev

L.Elmurodov

Tags

# acute toxicity# острая токсичность# белые беспородные мыши# white autologous mice# оқ зотсиз сичқон# дамлама# настой# infusion# ўткир токсиклик# зопник коровяковидный произраста# Phlomis thapsoides growing in Uz# қўзи қулоқ Ўзбекистон ҳудудида ў

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Article Identifiers

ROI:

https://eroi.uz/11.0035/A1119-0127

DOI:

Not Available

References

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5. ГОСТ 12.1.007-76. Система стандартов безопасности труда. Вредные вещества. Классификация и общие требования безопасности. – Москва: ФГУП «Стандартинформ», 2007. – 7 с.