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THE EFFECTS OF POLYPHENOL GOSSITAN ON THE PASSIVE ION PERMEABILITY OF MITOCHONDRIA MEMBRANES IN ALLOXAN DIABETES

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ARTICLE ANNOTATION

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It was studied the effect of polyphenol gossitan, isolated from the plant Gossypium hirsutuim hypoglycemic properties on the passive permeability of the membranes for single and double-valentcations of rat liver mitochondria under conditions of normal and alloxan diabetes in in vivo experiments. The has been shown increase of passive permeability of mitochondrial membranes for single and double-valent cations in under condition of alloxan diabetes was demonstrated. Pharmacotherapy of gossitan laboratory animals with diabetes showed the change and correction of passive permeability of mitochondrial membranes for single and double-valentcations.

AUTHORS

S.Aminov

M.Pozilov

A.Rahimov

R.Mahmudov

M.Asrorov

Tags

# жигар митохондриялари# госситан# пассив ўтказувчанлик# аллоксан# liver mitochondria# gossitan# passive permeability# alloxan# митохондрии печени# пассивная проницаемость

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Article Identifiers

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https://eroi.uz/11.0035/A1119-0085

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Not Available

References

1. Абдулладжанова Н.Г., Мавлянов С.М., Салихов Ш.И., Камаев Ф.Г. Новые полифенольние соединение сем. Euphorbiaceae // ДАН РУз. – 2011. – №3. – С. 60-62.

2. Позилов М.К, Эргашев Н.А., Асраров М.И., Рахматуллаева М.М., Аминов С.Н. Гликоразмулиннинг экспериментал диабет шароитида митохондрия мембраналари пассив ўтказувчанлигига таъсири // Фармацевтический журнал. – 2016. – №3.– Б. 99-103.

3. Шахмарданова С.А., Гулевская О.Н., Селецкая В.В., Зеленская А.В., Хананашвили Я.А., Нефедов Д.А., ГаленкоЯрошевский П.А., Антиоксиданты: классификация, фармакотерапевтические свойства, использование в практической медицине // Журнал фундаментальной медицины и биологии. – 2016. – №3. – С. 4-15 с

4. Bajaj S., Khan A. Antioxidants and diabetes // Indian J Endocrinol Metab. – 2012. – V.16(2). – P. 267-271.

5. Borisova M.P., Kataev A.A., Mavlyanov S.M., Abdullajanova N.G. Effects of hydrolysable tannins on native and artifcial biological membranes // Membrane and Cell Biology. – 2015. – V.9(1). – P. 53-60.

6. Kim H.S., Quon M.J., Kim J. New insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallate // Redox Biology. – 2014. – V.2. – P. 187-195.

7. Salakhutdinov B.A., Tukfatullina I.I., Ziyatdinova R.Kh., Tokhtaeva E.K., Mavlуanov S.M., Abdulladjanova N.G., Dalimov D.N., Aripov T.F. The antioxidant and antiradical properties of tannins extracted from different plant sourse //Uzbek biological Jornal, 2008, №2, P. 3-9. (03.00.00. №1).

8. Sandoval-Acuсa C., Ferreira J., Speisky H. Polyphenols and mitochondria: An update on their increasingly emerging ROS-scavenging independent actions // Archives of Biochemistry and Biophysics. – 2014. – V.559. – P. 75-90.

9. Szewczyk A., Wojtczak L. Mitochondria as a pharmacological target // Pharmacol Rev. – 2002. – 54(1). P. 101-127.