RELEASE OF ACTIVE INGREDIENTS FROM THE CAPSULE OF THE ANTI-TUBERCULOSIS DRUG "BIOMAYRIN"

The kinetics of the release of biologically active components from the capsule form "Biomayrin" has been studied. For this, methods such as «Dissolution» test and dialysis method were used. As a result of studies of various profiles in experiments, it was found that the most complete release was observed in the «Dissolution» test method. In the dialysis method, a slow but gradual release of the substances was observed, indicating that the polymeric carrier provides a long-lasting effect of isoniazid, rifampicin and ethambutol. The obtained results show that in the «Dissolution» method, the degree of release of biologically active substances after 1 hour is 81%, and in the dialysis regime after 48 hours - not less than 67.5%.