18

The combination of AH and diabetes increases the risk of coronary heart disease, stroke, kidney failure by 2-3 times. Therefore, it is extremely
important to recognize and diagnose both arterial hypertension and diabetes mellitus early, to prescribe the appropriate treatment in time and stop
the development of severe vascular complications. On the ionic level, insulin affects the entry of calcium and sodium into the cell, which affect the
contractility of vascular smooth muscle fibers. As a result of decreased insulin sensitivity, calcium influx into the cell increases and smooth muscle
cell tension increases. In such patients, the response of coronary arteries to physiological stimuli is reduced (decreased ability to dilate), which leads
to impaired microcirculation.

  • Read count 18
  • Date of publication 15-03-2022
  • Main LanguageIngliz
  • Pages55-57
English

The combination of AH and diabetes increases the risk of coronary heart disease, stroke, kidney failure by 2-3 times. Therefore, it is extremely
important to recognize and diagnose both arterial hypertension and diabetes mellitus early, to prescribe the appropriate treatment in time and stop
the development of severe vascular complications. On the ionic level, insulin affects the entry of calcium and sodium into the cell, which affect the
contractility of vascular smooth muscle fibers. As a result of decreased insulin sensitivity, calcium influx into the cell increases and smooth muscle
cell tension increases. In such patients, the response of coronary arteries to physiological stimuli is reduced (decreased ability to dilate), which leads
to impaired microcirculation.

№ Name of reference
1 1. Aghababyan I.R., Sadykova Sh. Sh., Ruzieva A.A. Assessment of patients who suffered myocardial infarction complicated by chronic heart failure against the background of taking cardioprotectors // Advances in Science and Education. - 2020. - №. 2 (56). 2. Xabibovna Y. S., Buriboevich N. M. SOME FEATURES OF STRUCTURAL AND FUNCTIONAL CHANGES OF THE MYOCARDIAL IN PATIENTS WITH DIABETES MELLITUS WITH DIASTOLIC HEART FAILURE //E-Conference Globe. - 2021. - P. 208-211. 3. Habibovna Y. S. et al. Assessment of Structural and Functional Heart Changes in Patients with Diabetes Mellitus with Diastolic Heart Failure //Annals of the Romanian Society for Cell Biology. - 2021. - С. 12154-12159. 4. Alisherovna M. K., Erkinovna Z. K., Tatlibayevich S. Y. Liver Diseases in Pregnant Women, Principles of Treatment //Eurasian Research Bulletin. - 2022. - Т. 4. - С. 48-51. 5. Yarmukhamedova S. et al. Značilnosti diastolične disfunkcije desnega prekata pri bolnikih s hipertonično boleznijo //Journal of Advanced Medical and Dental Sciences Research. - 2020. - Т. 8. - №. 9. - С. 74-77. 6. Alisherovna K. M., Davranovna M. H., Nizametdinovich K. S. Chronic Heart Failure in Women //CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCES. - 2022. - Vol. 2. - No. 7. - P. 21-25. 7. Alisherovna K. M., Djamshedovna K. D., Kayumovna A. S. Evaluate the Quality of Life using the KDQOL-SFTM Questionnaire //CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCES. - 2022. - Т. 2. - №. 7. - С. 26-31. 8. Yarmukhamedova S. et al. Study of intracardiac hemodynamic parameters and myocardial structural state during monotherapy of arterial hypertension patients with moxonidine // Journal of Advanced Medical and Dental Research. - 2020. - Т. 8. - №. 9. - С. 78-81. 9. Bekmuradova M.S., Makhmudova Kh. D., Nazarov F.Y. DIAGNOSTIC SIGNIFICANCE OF MOSCOW NATRIYURETIC PEPTYDESCRIPTION OF CHRONIC HEART DEFECTS //Scientific progress. - 2021. - Т. 2. - №. 1. - С. 810-814.
Waiting