Relating to dietary gluten found in wheat, rye, and barley, celiac disease is an immune-mediated enteropathy and one of the most prevalent lifelong food-related disorders around the globe. In addition to enteropathy, celiac disease is also thought to be a systemic disorder marked by a variety of gluten-related signs and symptoms as well as disease-specific antibodies. When gluten is consumed, it produces toxic gluten peptides that can trigger both innate and adaptive immune responses in those who are susceptible.
Relating to dietary gluten found in wheat, rye, and barley, celiac disease is an immune-mediated enteropathy and one of the most prevalent lifelong food-related disorders around the globe. In addition to enteropathy, celiac disease is also thought to be a systemic disorder marked by a variety of gluten-related signs and symptoms as well as disease-specific antibodies. When gluten is consumed, it produces toxic gluten peptides that can trigger both innate and adaptive immune responses in those who are susceptible.
| № | Author name | position | Name of organisation |
|---|---|---|---|
| 1 | Djuraeva B.G. | !! | !! |
| 2 | Kasimova N.A. | !! | !! |
| 3 | Iznetaeva U.B. | !! | !! |
| № | Name of reference |
|---|---|
| 1 | Kelly CP (2018) Celiachia. In Malattie gastrointestinali ed epatiche. Fisiopatologia, diagnosi e trattamento (Sleisenger e Fordtran), II vol., C. 107, X ed., trad. ita, Edra Ed. Perrotta G (2021) The intestinal microbiota: towards a multifactorial integrative model. Eubiosis and dysbiosis in morbid physical and psychological conditions. Arch Clin Gastroenterol 7: 024-035. Link: https://bit.ly/3jJH6gb Perrotta G (2021) Intestinal dysbiosis: defi nition, clinical implications, and proposed treatment protocol (Perrotta Protocol for Clinical Management of Intestinal Dysbiosis, PID) for the management and resolution of persistent or chronic dysbiosis. Arch Clin Gastroenterol 7: 056-063. Link: https://bit.ly/3voWpjS Kasanda DD, Okita TW, Bernardin JE, Baecker PA, Nimmo CC, et al. (1984) Nucleic acid (cDNA) and amino acid sequences of alfa-type gliadins from wheat (Triticum aestivum). Proc Natl Acad Sci USA 81: 4712-4716. Link: https://bit.ly/3JP2uv3 El-Metwally A, Toivola P , AlAhmary K, Bahkali S, AlKhathaami A, et al. (2020) The epidemiology of Celiac Disease in the general population and high-risk group in arab countries: a systematic review. Biomed Res Int. Link: https://bit.ly/37WsyHd Ierodiakonou D, Garcia-Larsen V, Logan A, Groome A, Cunha S, et al. (2016) Timing of allergenic food introduction to the infant diet and risk of allergic or autoimmune disease: a systematic review and meta-analysis. JAMA 316: 1181-1192. Link: https://bit.ly/3JObiBa Safi MA (2019) Celiac disease among at-risk individuals in Saudi Arabia. Saudi Med J 40: 9-18. Link: https://bit.ly/3EjJhR2 Villanacci V, Vanoli A, Leoncini G, Arpa G, Salviato T, et al. (2020) Celiac disease: histology-differential diagnosis-complications. A practical approach. Pathologica 112: 186-196. Link: https://bit.ly/3KJDvum Ensari A, Marsh MN (2019) Diagnosing celiac disease: A critical overview. Turk J Gastroenterol 30: 389-397. Link: https://bit.ly/3KRxHyU Rugarli C (2021) Medicina Interna Sistematica.VIII ed., Edra Ed. Bamonte F (2012) Celiachia: nuove opportunità diagnostiche. Tesi di specializzazione in Biochimica clinica, Università degli Studi di Pisa. Crowe SE (2020) Putting celiac disease in perspective: Pathogenesis, comorbidity and transition of care. United European Gastroenterol J 8: 129- 130. Link: https://bit.ly/3uMlciz D’Avino P, Serena G, Kenyon V, Fasano A (2021) An updated overview on celiac disease: from immuno-pathogenesis and immuno-genetics to therapeutic implications. Expert Rev Clin Immunol 17: 269-284. Link: https://bit.ly/36oAVew Capittini C, De Silvestri A, Rebuffi C, Tinelli C, Poddighe D (2019) Relevance of HLA-DQB1*02 Allele in the genetic predisposition of children with celiac disease. Medicina (Kaunas) 55: 190. Link: https://bit.ly/3vnfnqX De Silvestri A, Capittini C, Poddighe D, Valsecchi C, Marseglia G, et al. (2018) HLA-DQ genetics in children with celiac disease: a meta-analysis suggesting a two-step genetic screening procedure starting with HLA-DQ β chains. Pediatr Res 83: 564-572. Link: https://bit.ly/3k1tzAV Garnier-Lengliné H, Cerf-Bensussan N, Ruemmele FM (2015) Celiac disease in children. Clin Res Hepatol Gastroenterol 39: 544-551. Link: https://bit.ly/3EhD8ok Vackovà Z (2020) Celiac disease in adults. Vnitr Lek 66: 116-120. Link: https://bit.ly/3MaGXi8 Jericho H, Sansotta N, Guandalini S (2017) Extraintestinal manifestations of Celiac Disease: Effectiveness of the Gluten-Free Diet. J Pediatr Gastroenterol Nutr 65: 75-79. Link: https://bit.ly/36oBhSo. |