Xerostomia, or dry mouth, is a common and often underestimated clinical condition that can significantly impair patients' quality of life. This condition can be associated with various diseases, as well as with the negative effects of medications used to treat them. This is especially important for patients with diseases of the cardiovascular system, as many of them receive medications that can cause changes in salivation.Symptoms of xerostomia include discomfort, difficulty swallowing and speaking, and an increased risk of dental disease. Despite the significant impact of xerostomia on the health of patients, the issues of its assessment and management remain insufficiently investigated. management
Xerostomia, or dry mouth, is a common and often underestimated clinical condition that can significantly impair patients' quality of life. This condition can be associated with various diseases, as well as with the negative effects of medications used to treat them. This is especially important for patients with diseases of the cardiovascular system, as many of them receive medications that can cause changes in salivation.Symptoms of xerostomia include discomfort, difficulty swallowing and speaking, and an increased risk of dental disease. Despite the significant impact of xerostomia on the health of patients, the issues of its assessment and management remain insufficiently investigated. management
№ | Author name | position | Name of organisation |
---|---|---|---|
1 | Ravshanova O.T. | ! | Tashkent State Dental Institute, |
№ | Name of reference |
---|---|
1 | 1.Archakov A.I. Ipatova O.M., Lisitsa A.M., Mashkovsky S.A. Safe medicines: myth or reality. 2016;(6):519-523.2.Yuan A, Woo SB. Adverse drug events in the oral cavity. Oral Surg Oral Med Oral Pathol OralRadiol. 2015;119:35-47. doi:10.1016/j.oooo.2014.09.009.3.Navazesh M, Kumar SK. Xerostomia: prevalence, diagnosis, and management. Compend Contin Educ Dent 2009;(30):326-328.4.Villa A, AbatiS. Risk factors and symptoms associated with xerostomia: a cross-sectional study. Aust Dent J. 2011;56:290-295. doi:10.1111/j.1834-7819.2011.01347.x.5.Gorobets S. M., Romanenko I. G., Jerelei A. A., Bobkova S. A., Kryuchkov D. Yu., Gorobets O. V. Dental aspects of the manifestation of undesirable drug reactions// Tavrichesky medico-biological bulletin, 2018; volume 21; No. 3;166-1816.Vinayak V., Annigeri R.G., Patel H.A., Mittal S. Adverse effects of drugs on saliva and salivary glands. J Orofac Sci 2013; 5:15-207.Belousov Yu.B., Gurevich KG. Clinical pharmacokinetics. The practice of drug dosing. —M.: Litera 2005. —288 p.8.Sergienko V.I., Jelliffe R., Bondareva I.B. Applied pharmacokinetics: basic principles and clinical application. Moscow: Publishing House of the Russian Academy of Medical Sciences, 2003. 208 p.9.Smith P.M. Edgar M., Dawes S., O'mullane D., ed. Saliva and Oral Health, 4th ed. London: Stephen Hancocks Ltd.; 2012. Mechanisms of saliva secretion; pp. 17-3610.Wong D.T. In: Wong D.T., ed. Salivarydiagnostics. Iowa: Wiley-Blackwell; 2008. pp. 14-37.11.Baum B.J., Wellner R.B. Salivary gland receptors. In: Garrett JR, Ekstrom J, Anderson LC, editors. Nervous mechanisms of salivary gland secretion. Basel: Karger; 1999. pp. 44-58. 12.Catalan M.A., NakamotoT., Melvin J.E. The mechanism of fluid secretion by salivary glands. J.M. Invest. 2009; 56 (Appendix): S192–S196.13.Humphrey S.P., Williamson R.T. Saliva review: normal composition, flow and function. Jay forgets Dent. 2001; 85 : 162-16914.Zolotukin S. Metabolic hormones of saliva: origin and functions. Oral Dis. 2013; 19 : 219-229.15.Villa A, Abati S. Risk factors and symptoms associated with xerostomia: a cross-sectional study. Aus Dent J. 2011; 56 : 290-29516.Ciancio S.G. The effect of drugs on oral health. J Am Dent Assoc. 2004; 135 : 1440-144817.Atkinson JC, Grisius M, Massey W. Hypofunction of the salivary glands and xerostomia: diagnosis and treatment. Dent Klin North Am. 2005; 49 : 309-326. |