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Panaxitriol and its derivatives are biologically active substances isolated from a natural product - red ginseng root. It was found that they are responsible for its main pharmacological properties, namely: cytotoxic, chemoprotective, chemopreventive, antiplatelet and anti-inflammatory. This review will consider the substrate for such a broad action.

  • Ўқишлар сони 0
  • Нашр санаси 21-03-2024
  • Мақола тилиIngliz
  • Саҳифалар сони776-781
English

Panaxitriol and its derivatives are biologically active substances isolated from a natural product - red ginseng root. It was found that they are responsible for its main pharmacological properties, namely: cytotoxic, chemoprotective, chemopreventive, antiplatelet and anti-inflammatory. This review will consider the substrate for such a broad action.

Муаллифнинг исми Лавозими Ташкилот номи
1 Akbarov N.A. student Tashkent Pharmaceutical Institute
Ҳавола номи
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2 2. Heedong Yun, Ting-Chao Chou, Huajin Dong, Yuan Tian, Yue-ming Li, and Samuel J. Danishefsky; Total Synthesis as a Resource in Drug Discovery: The First In Vivo Evaluation of Panaxytriol and Its Derivatives, 2005.
3 3. Fay Ng, Heedong Yun, Xiaoguang Lei, Samuel J. Danishefsky, Jed Fahey, Katherine Stephenson, Charles Flexner, Lawrence Lee; (3R, 9R, 10R) –
4 4. Panaxytriol: a molecular-based nutraceutical with possible application to cancer prevention and treatment; Columbia University ,, USA, 2008
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9 9. Bushma, M.I.Pharmacology. Part 2: for students of institutions of higher medical education / M.I.Bushma, K.M.Bushma. - Minsk Vysh. shk. 2013.- 464
10 10. C. Chou TC, Multifaceted cytoprotection by synthetic polyacetylenes inspired by the ginseng-derived natural product, panaxytriol. Proceedings of the National Academy of Sciences / Dong H, Zhang X, Lei X, Hartung J, Zhang Y, Lee JH, Wilson RM, Danishefsky SJ, - USA, 2011.
11 11. Constance Lay Lay Saw, Anti-cancer and potential chemopreventive actions of ginseng by activating Nrf2 (NFE2L2) anti-oxidative stress / anti-inflammatory pathways. Chinese Medicine / Wu Q. Tony Hong A. - China, 2010.
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