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It is known that in the genesis of thrombocytopenia important role identify genetic factors. Significant advances in the study of genetic polymorphisms for thrombocytopenia reveal many unknown aspects of the mechanism of the disease. However, most of these studies are conflicting data.This requires further research to study the role of genetic polymorphisms for thrombocytopenia

  • Ўқишлар сони 146
  • Нашр санаси 02-04-2018
  • Мақола тилиIngliz
  • Саҳифалар сони185-188
English

It is known that in the genesis of thrombocytopenia important role identify genetic factors. Significant advances in the study of genetic polymorphisms for thrombocytopenia reveal many unknown aspects of the mechanism of the disease. However, most of these studies are conflicting data.This requires further research to study the role of genetic polymorphisms for thrombocytopenia

Ўзбек

Маълумки, тромбоцитопениянинг генезида генетик омиллар муҳим аҳамиятга эга. Тромбоцитопенияда генетик полиморфизмларнинг анча муваффакиятли ўрганилиши касалликнинг ривожланиш механизмининг кўп ноаниқ томонларини очиб бермоқда. Аммо, бу изланишларнинг кўпчилиги карама карши маълумотларга эга. Бу эса ўз навбатида тромбоцитопенияда генетик полиморфизмларнинг аҳамиятини кейинги тадкикотларда чуқур ўрганишларни талаб қилмокда

Русский

Известно, что в генезе тромбоцитопении немаловажную роль определяют генетические факторы. Значительные успехи в изучении генетических полиморфизмов при тромбоцитопении раскрывают многие неизвестные стороны механизма развития заболевания. Однако, большинство этих исследований имеют противоречивые данные. Это требует проведение дальнейших исследований по изучению роли генетических полиморфизмов при тромбоцитопении.

№ Муаллифнинг исми Лавозими Ташкилот номи
1 Masharipova I.Y. UrDU
№ Ҳавола номи
1 Shumihin A.V. Clinic-lab datas of immune thrombocytopenia, associate with Неlicobacter Pylori. Autoreferat dissertation on candidate of medical science. Perm 2001. P 24.
2 Dogan M, Oner AF, Acikgoz M, Uner A. Treatment of chronic immune thrombocytopenic purpura with rituximab in children. //Indian J Pediatr. 2009 Nov; 76(11):1141-4
3 Noris P, Perrotta S, Ser M, et al. Mutations in ANKRD26 are responsible for a frequent from of inherited thrombocytopenia: analysis of 780 patients from 21 families// Blood 2011; 117(24):6673-6680.
4 Punzo F, Mientjes EJ, Rohe CF, et al. A mutation in the acyl-coenzyme A binding domain-containing protein 5 gene (ACBD5) identified in autosomal dominant thrombocytopenia.//J.thromb. Haemost (JTH) 2010; (9):2085-2087
5 Scully M, Brown J, Patel R Human leukocyte antigen association in idiopathic thrombotic thrombocytopenic purpura: evidence for an immunogenetic link. //J. Thromb Haemost. 2010 Feb; 8(2):257-62. Epub.
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