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Acute or chronic liver damage brought on by medicines or natural chemicals is known as drug-induced hepatotoxicity. The appearance is comparable to numerous hepatobiliary illnesses, making diagnosis challenging. The elimination of the offending agent and careful observation for resolution constitute the main treatment. The pathophysiology, assessment, and management of drug-induced hepatotoxicity are explained in this activity. It also discusses how the interprofessional team might help patients receive better care. Based on experimental validation, natural bioactive components generated from plant secondary metabolites have been pronounced as valuable options for predicting and mitigating hepatotoxic effects and their chronic consequences. This review aims to clarify the commonly used modern medicine for liver disease treatment, the hepatoprotective activity of major phytoconstituents, the mechanism of action of some promising natural agents, and the results of clinical trials for treating patients with various liver diseases using natural phytoconstituents. Even though a much greater number of plant species have been linked to hepatoprotective properties, the selection process was based on how well they were formulated and then incorporated into contemporarymedical systems. With the ultimate goal of identifying these plants as potential sources of novel hepatoprotective herbal medicines, the gathered data was also critically examined to offer insights and suggestions for further research

  • Ўқишлар сони 12
  • Нашр санаси 10-05-2025
  • Мақола тилиIngliz
  • Саҳифалар сони216-224
English

Acute or chronic liver damage brought on by medicines or natural chemicals is known as drug-induced hepatotoxicity. The appearance is comparable to numerous hepatobiliary illnesses, making diagnosis challenging. The elimination of the offending agent and careful observation for resolution constitute the main treatment. The pathophysiology, assessment, and management of drug-induced hepatotoxicity are explained in this activity. It also discusses how the interprofessional team might help patients receive better care. Based on experimental validation, natural bioactive components generated from plant secondary metabolites have been pronounced as valuable options for predicting and mitigating hepatotoxic effects and their chronic consequences. This review aims to clarify the commonly used modern medicine for liver disease treatment, the hepatoprotective activity of major phytoconstituents, the mechanism of action of some promising natural agents, and the results of clinical trials for treating patients with various liver diseases using natural phytoconstituents. Even though a much greater number of plant species have been linked to hepatoprotective properties, the selection process was based on how well they were formulated and then incorporated into contemporarymedical systems. With the ultimate goal of identifying these plants as potential sources of novel hepatoprotective herbal medicines, the gathered data was also critically examined to offer insights and suggestions for further research

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