Ma’lumki, ichak mikrobiotasi bir qancha omillarga, shu jumladan antibiotiklarga ta’sir qiladi va xoʻjayinning sogʻligi uchun muhim rol oʻynaydi. Antibiotiklarni qoʻllash tufayli esa mikroorganizmlar tarkibidagi oʻzgarishlar xoʻjayinning sogʻligʻiga zarar yetkazishi mumkin. Ushbu oʻzgarishlar mikroblarning xilma-xilligini kamaytirish, mikrobiota funktsiyalarining oʻzgarishi va antibiotiklarga chidamli shtammlarni yaratish va koʻpaytirishni oʻz ichiga oladi, bu esa clostridioides difficile kabi patogenlar bilan infektsiyaga ko'proq moyil qiladi. Antibiotiklarga qarshilik global inqirozni anglatadi va antibiotiklardan foydalanish vaqt oʻtishi bilan oʻsishda davom etar ekan, ularning mikrobiota va inson salomatligiga ta’sirini oʻrganish zarurati tugʻiladi. Ushbu taqdim etlgan sharhda antibiotiklarning ichak mikrobiotasiga va shuning uchun inson sogʻligi uchun salbiy ta’siri qisqacha muhokama qilingan va shuningdek antibiotiklardan foydalanishning muqobil usullarini taklif qilingan
Ma’lumki, ichak mikrobiotasi bir qancha omillarga, shu jumladan antibiotiklarga ta’sir qiladi va xoʻjayinning sogʻligi uchun muhim rol oʻynaydi. Antibiotiklarni qoʻllash tufayli esa mikroorganizmlar tarkibidagi oʻzgarishlar xoʻjayinning sogʻligʻiga zarar yetkazishi mumkin. Ushbu oʻzgarishlar mikroblarning xilma-xilligini kamaytirish, mikrobiota funktsiyalarining oʻzgarishi va antibiotiklarga chidamli shtammlarni yaratish va koʻpaytirishni oʻz ichiga oladi, bu esa clostridioides difficile kabi patogenlar bilan infektsiyaga ko'proq moyil qiladi. Antibiotiklarga qarshilik global inqirozni anglatadi va antibiotiklardan foydalanish vaqt oʻtishi bilan oʻsishda davom etar ekan, ularning mikrobiota va inson salomatligiga ta’sirini oʻrganish zarurati tugʻiladi. Ushbu taqdim etlgan sharhda antibiotiklarning ichak mikrobiotasiga va shuning uchun inson sogʻligi uchun salbiy ta’siri qisqacha muhokama qilingan va shuningdek antibiotiklardan foydalanishning muqobil usullarini taklif qilingan
The gut microbiota is known to influence several factors, including antibiotics, and plays an important role in host health. However, due to the use of antibiotics, changes in the composition of microorganisms can harm the health of the host. These changes include a decrease in microbial diversity, changes in the functions of the microbiota, and the creation and reproduction of antibiotic-resistant strains that make them more susceptible to infections by pathogens such as Clostridioides difficile. Antibiotic resistance is a global crisis, and as the use of antibiotics continues to grow over time, there is a need to study their effects on the microbiota and human health. This presented review briefly discusses the negative effects ofantibiotics on the gut microbiota and, consequently, on human health, and suggests alternative ways to use antibiotics.
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