Arnica montana(also called wolf’s bane) is a tall perineal plant with large yellow flowers that belongs to the daisy family Asteraceae and is widespread across Europe. Arnica montana is used in small oral doses in homeopathic medicine and in low doses as treatment for pain, inflammation and fever, most often post-surgery or trauma. It is also used more conventionally as a topical medication for wound healing, swelling, inflammation, bruising and pain. However, there is little evidence for its efficacy either as an oral homeopathic or a topical herbal therapy. The FDA classifies Arnica montana as an unsafe herb and cautions against using it orally or applied to broken skin where absorption can occur. Arnica montana extracts have antiinflammatory effects in vitro and have been purported to be beneficial for pain and swelling when applied topically. The clinical studies have not confirmed its effects on inflammation or pain. Arnica montana is available in multiple over-the-counter topical forms which are claimed to be usefulin treating painful skin conditions. Arnica montana extracts applied topically have mild-to-moderate adverse events, which usually overwhelm any beneficial effects they may have on skin conditions. Oral administration of Arnica montana in moderate amountscan cause gastrointestinal upset, nausea, vomiting and abdominal pain. Arnica montana extracts can cause skin rash and urticaria and should not be taken by mouth.
Arnica montana(also called wolf’s bane) is a tall perineal plant with large yellow flowers that belongs to the daisy family Asteraceae and is widespread across Europe. Arnica montana is used in small oral doses in homeopathic medicine and in low doses as treatment for pain, inflammation and fever, most often post-surgery or trauma. It is also used more conventionally as a topical medication for wound healing, swelling, inflammation, bruising and pain. However, there is little evidence for its efficacy either as an oral homeopathic or a topical herbal therapy. The FDA classifies Arnica montana as an unsafe herb and cautions against using it orally or applied to broken skin where absorption can occur. Arnica montana extracts have antiinflammatory effects in vitro and have been purported to be beneficial for pain and swelling when applied topically. The clinical studies have not confirmed its effects on inflammation or pain. Arnica montana is available in multiple over-the-counter topical forms which are claimed to be usefulin treating painful skin conditions. Arnica montana extracts applied topically have mild-to-moderate adverse events, which usually overwhelm any beneficial effects they may have on skin conditions. Oral administration of Arnica montana in moderate amountscan cause gastrointestinal upset, nausea, vomiting and abdominal pain. Arnica montana extracts can cause skin rash and urticaria and should not be taken by mouth.
| № | Имя автора | Должность | Наименование организации |
|---|---|---|---|
| 1 | Mamatkulov Z.U. | associate professor | Tashkent Pharmaceuticals Institute |
| 2 | Sharipova R.T. | assistant teacher | Tashkent Pharmaceuticals Institute |
| № | Название ссылки |
|---|---|
| 1 | Zimmerman HJ. Unconventional drugs. Miscellaneous drugs and diagnostic chemicals. In, Zimmerman, HJ. Hepatotoxicity: the adverse effects of drugs and other chemicals on the liver. 2nd ed. Philadelphia: Lippincott, 1999: pp. 731-4..2.Liu LU, Schiano TD. Hepatotoxicity of herbal medicines, vitamins and natural hepatotoxins. In, Kaplowitz N, DeLeve LD, eds. Drug-induced liver disease. 2nd ed. New York: Informa Healthcare USA, 2007, pp. 733-54. 3.Tveiten D, Bruset S. Effect of Arnica D30 in marathon runners. Pooled results from two double-blind placebo controlled studies. Homeopathy. 2003;92:187–9.4.Gazim ZC, Rezende CM, Fraga SR, Dias Filho BP, Nakamura CV, Cortez DAG. Analysis of the essential oilsfrom Calendula officinalis growing in Brazil using three different extraction procedures. Revista Brasileira de Ciências Farmacêuticas. 2008; 44(3): 391-395.5.Shahane, K., Kshirsagar, M., Tambe, S., Jain, D., Rout, S., Martins Ferreira, M. K., Mali, S., Amin, P., Srivastav, P. P., Cruz, J., & Lima, R. R. (2023). An Updated Review on the Multifaceted Therapeutic Potential of Calendula officinalis L. Pharmaceuticals, 16(4). https://doi.org/10.3390/ph16040611 Butnariu M, Coradini CZ. Evaluation of BiologicallyActive Compounds from Calendula officinalis Flowers using Spectrophotometry. Chem Cent J. 2012 Apr 27;6:35. doi: 10.1186/1752-153X-6-35. PMID: 22540963; PMCID: PMC3379952.7.Ak, G., Zengin, G., Ceylan, R., Mahomoodally, M. F., Jugreet, S., Mollica, A., & Stefanucci, A. (2021). Chemical composition and biological activities of essential oils from Calendula officinalis L. Flowers and leaves. Flavour and Fragrance Journal, 36(5), 554-563. https://doi.org/10.1002/ffj.36618.Arora D, Rani A, Sharma A. A review on phytochemistry and ethnopharmacological aspects of genus Calendula. Pharmacogn Rev. 2013; 7(14): 179.9.Safdar W, Majeed H, Naveed I, et al. Pharmacognostical study of the medicinal plant Calendula officinalis L. (family Compositae). Int. J Cell Mol Biol. 2010; 1: 108-116.10.Control methods. Chemical factors. Guide to methods of quality control and safety of biologically active food additives. Manual R 4.1.1672-03. M.: Federal Center for State Sanitary and Epidemiological Supervision of the Ministry of Health of Russia, 2004. |