15

Despite the use of modern treatments for patients with RA, the incidence of anemia, unwanted complications, and disability in the working population remains very high. The purpose of the study is to improve the principles of proportional treatment, taking into account the structure of anemia in rheumatoid arthritis, its occurrence, and haptoglobin phenotypes. In 2016-2020, a total of 214 patients treated with a diagnosis of rheumatoid arthritis in the cardiorheumatology department of the Samarkand City Medical Association and 20 relatively healthy people as a control group were selected for the study. Examination of patients was carried out using generally accepted clinical, laboratory, and instrumental methods. Changes in iron metabolism parameters are observed in RA patients and are more pronounced in patients with anemia, and such changes depend on the degree of anemia.

  • Количество прочтений 15
  • Дата публикации 01-11-2024
  • Язык статьиIngliz
  • Страницы26-32
English

Despite the use of modern treatments for patients with RA, the incidence of anemia, unwanted complications, and disability in the working population remains very high. The purpose of the study is to improve the principles of proportional treatment, taking into account the structure of anemia in rheumatoid arthritis, its occurrence, and haptoglobin phenotypes. In 2016-2020, a total of 214 patients treated with a diagnosis of rheumatoid arthritis in the cardiorheumatology department of the Samarkand City Medical Association and 20 relatively healthy people as a control group were selected for the study. Examination of patients was carried out using generally accepted clinical, laboratory, and instrumental methods. Changes in iron metabolism parameters are observed in RA patients and are more pronounced in patients with anemia, and such changes depend on the degree of anemia.

№ Имя автора Должность Наименование организации
1 Pulatov U.S. PhD, доцент !
2 Kobilov U.A. ! !
3 Shodikulova G.Z. DcS, профессор !
№ Название ссылки
1 Aletaha D, Blüml S. Therapeutic implications of autoantibodies in rheumatoid arthritis. RMD Open. 2016 May 17;2(1):e000009. doi: 10,1136/rmdopen-2014-000. Baillet A, Gossec L, Carmona L, et al. Points to consider for reporting, screening for and preventing selected comorbidities in chronic inflammatory rheumatic diseases in daily practice: a EULAR initiative. Ann Rheum Dis 2016;75:965–73. doi:10,1136/annrheumdis-2016-209233. Edwards CJ, Fautrel B, Schulze-Koops H, Huizinga TW, Kruger K. Dosing down with biologic therapies: a systematic review and clinicians perspective. Rheumatology (Oxford) 2017 Feb 16. doi: 10,1093/rheumatology/kew464. Padjen I., Ohler L., Studenic P., Woodworth T., Smolen J., Aletaha D. Clinical meaning and implications of serum hemoglobin levels in patients with rheumatoid arthritis. Semin. Arthritis Rheum. 2017; 47(2):193-198. https://doi.org/10.1016/j.semarthrit.2017.03.001 Александрова E.H. Иммунопатология ревматоидного артрита // Александрова E.H., Насонов Е.Л. // В кн. Авдеева A.C. (и др.): под ред. Насонова Е.Л. - М.: Изд. группа «ИМА-ПРЕСС», 2013. - 549с. Бабаева А.Р., Калинина Е.В., Каратеев Д.Е. Опыт применения тофацитиниба в лечении резистентного ревматоидного артрита // Современная ревматология, 2015, 2: 28-32. Ватутин Н.Т., Калинкина Н.В., Смирнова А.С. Анемия при ревматоидном артрите // Вестник Харьковского национального университета имени В.Н. Каразина. Серия «Медицина» 2010 №898 стр 76-82 Галушко Е.А., Эрдес Ш.Д., Амирджанова B.Н. Особенности диагностики ревматоидного артрита в реальной клинической практике // Научно-практическая ревматология, 2011. - №1. - С.21-26. Иголкина Е.В. (и др.) Возможность применения лефлуномида при ревматических заболеваниях // Современная ревматология, 2011. - №1. - С.54-57. Каратеев Д.Е. Острые вопросы стратегии лечения ревматоидного артрита // Современная ревматология, 2015, 1: 84-92. Пулатов У., Нематуллаев Ж., Шопулотова З. ОСТРЫЕ РЕСПИРАТОРНЫЕ ВИРУСНЫЕ ИНФЕКЦИИ: СИМПТОМЫ, ЛЕЧЕНИЕ И ПРОФИЛАКТИКА //Евразийский журнал медицинских и естественных наук. – 2024. – Т. 4. – №. 5. – С. 269-273. Шодикулова Г. З. и др. СОВРЕМЕННЫЙ ВЗГЛЯД НА ПРОБЛЕМУ АРТЕРИАЛЬНОЙ ГИПЕРТЕНЗИИ У БОЛЬНЫХ С ПОДАГРОЙ И БЕССИМПТОМНОЙ ГИПЕРУРИКЕМИЕЙ //Journal of cardiorespiratory research. – 2023. – Т. 1. – №. 1. – С. 28-33. Pulatov U., Hamdullaev M. LUS THERAPY IN PREGNANT WOMEN WITH CHRONIC RHINOSINUSITIS //Естественные науки в современном мире: теоретические и практические исследования. – 2022. – Т. 1. – №. 18. – С. 37-40. Pulatov U., Nematullayev J. MODERN VIEWS ON CHRONIC DISEASES OF THE UPPER RESPIRATORY TRACT IN PREGNANT WOMEN //Евразийский журнал медицинских и естественных наук. – 2024. – Т. 4. – №. 3. – С. 116-119. Shodikulova G. Z. et al. The Correlation among Osteoporosis, Calcium-Phosphore Metabolism and Clinical Symptoms of Main Disease in Patients with Rheumatoid Arthritis //Annals of the Romanian Society for Cell Biology. – 2021. – С. 4185-4190.
В ожидании