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The introduction comprehensively highlights the problem ofthe relationship between melatonin and Alzheimer's disease, including epidemiological data, current understanding of the pathogenesis and therapeutic perspectives. The text is structured logically, emphasizes the relevance of the problem and outlines the prospects for further research, while maintaining the scientific style of presentation and the accuracy of formulations

  • Количество прочтений 14
  • Дата публикации 08-03-2025
  • Язык статьиIngliz
  • Страницы 80-85
Ключевые слова
English

The introduction comprehensively highlights the problem ofthe relationship between melatonin and Alzheimer's disease, including epidemiological data, current understanding of the pathogenesis and therapeutic perspectives. The text is structured logically, emphasizes the relevance of the problem and outlines the prospects for further research, while maintaining the scientific style of presentation and the accuracy of formulations

Ключевые слова
№ Название ссылки
1 1.Baydas G., Reiter R.J., Akbulut M. Melatonin inhibits neural apoptosis induced by homocysteine inhippocampus of rats via inhibition of cytochrome c translocation and caspase-3 activation and by regulating pro-and anti-apoptotic protein levels. Neuroscience 2005; 135: 3: 879-886.2.Baydas G., Yasar A., TuzcuM. Comparison of the impact of melatonin onchronic ethanol-induced learning and memory impairment between young and aged rats. J Pineal Res 2005; 39: 4: 346-352.3.Den Heijer T., Greelings I., Hoebeek F. et al. Use of hippocampal and amygdaloid volumes on magnetic resonance imaging to predict dementia in cognitively intact elderly people. Arch Gen Psychiat 2006; 63: 1: 57-62.4.Dickerson B.C., Salat D.H., Greve D.N. et al. Increased hippocampal activation in mild cognitive impairment compared to normal aging and Alzheimer`s disease. Neurology 2005; 65:3: 404-411.5.Harderland R. Antioxidative protection by melatonin —multiplicity of mechanism from radical detoxication to radical avoidance. Endocrine 2005; 27: 119-130.6.Lee S.-H., Chun W., Kong P. et al. Sustained activation of Akt by melatonin contributes to the protection against kainic acid-induced neuronal death in hippocampus. J Pineal Res 2006; 40: 79-85.7.Li X.C., Wang Z.F., Zhang J.X. et al. Effect of melatonin on calyculin-Ainduced tau hyperphosphorylation. Eur J Pharmacol 2005; 510: 25-30.8.MaharajD.S., Maharaj H., Antunes E.M. et al. 6-Hydroxymelatonin protects against quinolic-acid-induced oxidative neurotoxicity in the rat hip-pocampus. J Pharm Pharmacol 2005; 57: 7: 877-881.9.Ozdemir D., Tugyan K., Uysal K. et al. Protective effect of melatoninagainst head trauma-induced hippocampal damage and spatial memory deficits in immature rats. Neurosci Lett 2005; 383: 3: 234-239.10.Pandi-Perumal S.R., Zisapel N., Srinivasan V. et al. Melatonin and sleep aging population. Exp Gerontol 2005; 40: 911-925.11.Quinn J., Kulhanek D., Nowin J. et al. Chronic melatonin therapy fails to alter amyloid burden or oxidative damage in old Tg 2576 mice: implications for clinical trials. Brain Res 2005; 1037: 209-213.12.Rakhmonova H.N., Rakhmonov Z.M. Innervation Relationshipsof the Gallbladder Nerve Apparatus with Spinal and Rheumatic Nerve Ganglia (Literature Review).Eurasian Medical Research Periodical,18, 105-108.13.Rakhmonova Kh.N. Morphological bases of innervational connections of the nervous apparatus of the gallbladder Journal of Problems in Biology and Medicine, PBIM 2022 No6 (140), 387-392.14.Savaskan E., Ayoub M.A., Ravid R. et al. Reduced hippocampal MT2 melatonin receptor expression in Alzheimer`s disease. J Pineal Res 2005; 38: 10-16.15.Vega-Naredo I., Poggeler B., Sierra-Sanchez V. et al. Melatonin neutralizes neurotoxicity induced by quinolinic acid in brain tissue culture. J Pineal Res 2005; 39: 266-275.16.Арушанян Э.Б. Гормон эпифиза мелатонин —новое ноотропное средствo? Экспер и клин фармакол 2005; 68: 3: 74-79.17.Арушанян Э.Б. Уникальный мелатонин. Ставрополь 2007; 399.18.Арушанян Э.Б. Хронобиологическая природа нарушений познавательной деятельности мозга. Журн неврол и психиат 2005; 105: 11: 73-78.19.Арушанян Э.Б., БейерЭ.В. Ноотропные свойства препаратов Гинкго билоба. Экспер и клин фармакол 2008; 71: 4: 57-63.20.Левин Я.И. Мелатонин (мелаксен) в трапии инсомнии. Рус мед журн 2005; 13: 7: 1-3.21.Яхно Н.Н., Преображенская И.С. Болезнь Альцгеймера: клиника, патогенез, лечение. Рус мед журн 2006; 14: 9: 641-646.
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