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РЕЗУЛЬТАТЫ СКРИНИНГА ПО РАННЕМУ ВЫЯВЛЕНИЮ СИНДРОМА КУШИНГА В ГРУППАХ РИСКА ВНАМАНГАНСКОЙ, КАШКАДАРЬИНСКОЙ И ХОРЕЗМСКОЙ ОБЛАСТЯХ РЕСПУБЛИКИ УЗБЕКИСТАН

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MAQOLA ANNOTATSIYASI

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The aim of study was to reseach the results of screening at risk groups of early detection of Cushing syndrome in Namangan, Kaskadarya and Khorezm regions of Uzbekistan. In total at the pilot regions of the Republic of Uzbekistan: Khorezm, Namangan and Kashkadarya regions 21,990 persons were undergone to CS screening and they were included in the applied project, of which 2,185 people were selected for further examination. From 2,185 patients men were 639 (29.2%), women were 1546 (70.7%). In the risk groups of patients were from Khorezm, Namangan and Kashkadarya regions, in the predominant majority, ldegree of obesity was (26.0%). The determination of cortisol in saliva revealed the following changes in our patients: 385 patients’ (17.6%) the saliva cortisol was higher than normal (Khorezm and Kashkadarya regions), and in urine it was in 198 (9%) patients (Namangan region). In total 583 people showed the increase cortisol in saliva / urine. (26.6%). Of these, the significant difference was found at control between BMI and elevated mean of salivary cortisol at 175 patients aged from 36 to 45 years. The determination of cortisol in saliva / urine were the qualitative indices at screening of Cushing’s syndrome in risk groups.

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# скрининг# Кушинг синдроми# эндоген ги- перкортицизм# Cushing syndrome# endogen hypercorticism# screening

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