Background. As a result of development of all industries brunches a comprehensive research and development of technologies for the enrichment and processing of demanded graphite ores for the purpose of obtaining graphite is of importance. In this respect, graphite ores of the Tuskazgan deposit of the Bukhara region, which need enrichment, are of great interest as raw materials. Purpose is to choose the method of enrichment of the graphite ore of the Tuskazgan deposit by the example of concentrating plants of other countries. Experimental way to select the optimal composition of flotation agents for the enrichment of graphite ores of the Tuskazgan deposit. Methodology. At laboratory researches the flotation was carried out on a mechanical flotation machine of FML-12 trademark. Milling and classification of graphite ore samples were carried out using standard laboratory equipment, according to a standard procedure. Originality. The optimum composition of flotation agents was obtained by comparing mixtures prepared from different quantities of collectors and blowing agents that showed the best results in the flotation of graphite ores. The kinetics of grinding of graphite ore from the Tuskazgan deposit of the Bukhara region Findings. To determine the optimum composition of flotation agents tabular graphite concentrate yield data with different collectors and foams are given. It was found that the optimal yield of graphite grade ore - 0.074 mm is 65 and more percent when grinding it for 10 minutes. Keywords: Graphite ore, flotation, collector, foaming agent, enrichment, flotation machine, kinetics of grinding. Highlights: - kinetics of grinding of graphite ore of the Tuskazgan deposit was studied; - the optimal composition of flotation agents was determined by experiment; - the optimum concentration of flotation reagents was determined.