ВЗАИМОСВЯЗЬ ВАРИАБЕЛЬНОСТИ РИТМА СЕРДЦА И ЖЕЛУДОЧКОВОЙ ЭКСТРАСИСТОЛИИ ПРИ СИСТОЛИЧЕСКОЙ ДИСФУНКЦИИ ЛЕВОГО ЖЕЛУДОЧКА У БОЛЬНЫХ С ИНФАРКТОМ МИОКАРДА

This study includes 84 male patients with acute Q-wave myocardial infarction. All the patients underwent echocardiography on the 10–14 day of disease in order to estimate systolic function of the left ventricle, ECG Holter monitoring with measurement of heart rate variability and ventricular extrasystole. All patients received standard therapy including β-blockers, antiagregants, antiarrhythmic agents, aldosteron antagonists, ACE inhibitors, calcium antagonists, nitrates, statins. After the first clinical-functional examination there was found systolic dysfunction of the left ventricle in 23 (27,4 %) patients. The development of the early left ventricle remodeling, acute heart failure, increasing level of inflammation markers were noted more frequently in this group of patients. We revealed that interrelation between heart rate variability and ventricular arrhythmia had reliable character in systolic dysfunction.