КЛИНИКО-ФУНКЦИОНАЛЬНЫЕ ОСОБЕННОСТИ ПАЦИЕНТОВ С ДЕКОМПЕНСИРОВАННОЙ ХСН В ЗАВИСИМОСТИ ОТ ИСХОДНОГО УРОВНЯ ST2

Objective: to conduct a comparative assessment of the clinical and functional state of patients admitted to hospital for the development of decompensation of heart failure, depending on the initial level of ST2. Materials and methods. The study included 40 patients with decompensated heart failure. Depending on the level of ST2 at admission, patients were divided into 2: a group with an ST2 level ≤ 30,0 ng /ml and a group with an ST 2 level of more than 30,0 ng/ml. The following were analyzed: personal data, clinical status, parameters of central and intracardiac hemodynamics, indicators of renal function, CRP. Results. In patients with an ST2 level of more than 30,0 ng/ml, the duration of heart failure was significantly longer (36,95 ± 15,38 versus 24,95 ± 12,38, relatively 2 groups), and the number of hospitalizations per year was more frequent. This group is characterized by low compliance, central hemodynamics, with a high heart rate, worse functional indices in terms of 6MWT, and low MQoL. The parameters of the echocardioscopic examination in the two groups were comparable without significant difference between themselves. In the group with an ST2 level of more than 30 ng/ml, higher creatinine values were noted. The level of CRP also was significantly higher in the 2nd group. Conclusions. Thus, the presence of elevated ST2 levels in patients with decompensated heart failure is a significant marker of the worse course of heart failure, regardless of the etiology of the disease.