
Relevance. In cardiology, in conditions of comorbidity of chronic heart failure (CHF) with anxiety-depressive disorders (ADD), a fundamentally new and very relevant clinical problem is born, requiring new approaches to the diagnosis and treatment of this category of patients. Objective. study of the frequency and structure of neurotic level АDD in patients with heart failure with different left ventricular ejection fraction (LVEF). Маterial and methods. 120 patients with CHF aged 42 to 72 years were examined using the Clinical State Assessment Scale, 6-minute walk test, ultrasound of the heart, hospital anxiety and depression scale (HADS), Minnesota Quality of Life Questionnaire (МLHFQ). Results. A comparative analysis of the results obtained in patients with CHF depending on LVEF (low, intermediate, preserved), as well as the presence and severity of АDD, showed that the clinical signs and functional class of heart failure, structural and functional changes in the heart, severe depression with a decrease in the quality of life were more often and more significant in patients with heart failure with low LVEF. At the same time, anxiety and better quality of life indicators prevailed in patients with chronic heart failure with preserved LVEF, and with intermediate LVEF the above indicators occupied an intermediate position. Conclusions: There is a close relationship between the severity of heart failure, LVEF indicators and the frequency and severity of АDD. Severe depression and low quality of life are associated in patients with heart failure with low levels of LVEF. In patients with chronic heart failure with intermediate and preserved LVEF, prevail mixed ADD against the background of somewhat better indicators of quality of life.