ОСОБЕННОСТИ ЛИПИДНОГО СПЕКТРА, ВНУТРИСЕРДЕЧНОЙ ГЕМОДИНАМИКИ И РЕЗУЛЬТАТОВ КОРОНАРОАНГИОГРАФИИ У БОЛЬНЫХ ИБС СО СМЕШАННОЙ ДИСЛИПИДЕМИЕЙ

Objective: To study features of lipid metabolism, intracardiac hemodynamics and results of coronary angiography in ischemic heart disease patients with mixed dyslipidemia. Materials and methods: The study included 88 patients with unstable angina, and dyslipidemia (LDL-C ≥ 100 mg / dL). According to level of triglycerides (TG) all patients were divided into 3 groups: TG < 200 mg / dL, 2nd group: TG ≥ 200 mg / dL, 3rd-group: TG ≥ 300 mg / dL. Assessment of lipid metabolism was performed on biochemical analyzer “Randox” (UK). Results: Among patients with dyslipidemia (DLP) IIB, with TG levels > 300 mg / dl diabetes was significantly more frequent, had higher body mass index and atherogenic factor in significantly lower values of HDL cholesterol, compared with the group of patients with type IIA DLP. The results of coronary angiography show a higher frequency of multivessel disease in patients with DLP type IIB (6 patients in the 2nd and 6 in 3rd group), in total, 12 (20.3 %) of 59, whereas in 1st group indicated lesion observed twice at least – only in 3 (10.3 %) of the 29 examined, although the difference was of character in general. Conclusion: In patients with dyslipidemia IIB, was significantly more common diabetes, had higher body mass index, and the atherogenic index, with significantly lower values of HDL cholesterol, compared with patients who have dyslipidemia IIA. At the same time in patients with dyslipidemia IIB 2 times more often observed multivessel coronary artery disease (20.3 %) than among patients with dyslipidemia IIA, which requires further study.