Взаимосвязь гипогликемии с клиническими особенностями течения саха рного диабета 2 типа

Objective: to study the frequency of hypoglycemia in patients with an equal level of HbA1c, to compare the clinical and anamnestic characteristics of patients with frequent episodes of hypoglycemia Materials and methods: 53 patients with IHD and type 2 diabetes entered the study. Along with general clinical studies, all patients underwent simultaneous monitoring of ECG and glycemia for 14 days. Continuous ECG monitoring was performed using the SR-Medizinelektronik wearable device SRA + V2. Continuous monitoring of glycemia in patients was carried out using the portable Continuous Glucose Monitoring System – the continuous glucose monitoring system (GMS) of Abbot (USA), which consists of three main parts: a sensor, a monitor, and a computer data transfer device. The principle of operation of SNMG is based on the glucose oxidase method. The monitor samples signals every 10 seconds and records the average signal every minutePatients once filled a hypoglycemia recognition questionnaire, consisting of 10 questions and gradations never, rarely, sometimes, often. According to the results of continuous monitoring of glycemia, patients were divided into two groups depending on the frequency of occurrence of episodes of hypoglycemia: the proportion of hypoglycemia is less than 4% and ≥4%. Results and discussion: In patients with diabetes, with a comparable value of the HbA1c indicator, a different frequency of episodes of hypoglycemia is observed. An association of episodes of hypoglycemia with the severity of diabetic nephro- and encephalopathy was revealed. The use of the new hypoglycemia questionnaire contributed to the accurate differentiation of patients with frequent episodes of hypoglycemia The tendency for an increase in VES and AF with hypoglycemia was determined; according to the data obtained, they require further analysis and confirmation in a larger sample of patients