Клинические особенности течения ишемической болезни сердца у больных с эрозивно-язвенным и пораж енияМИ гастродуоденальной зоны

Cardiovascular diseases (CVD), and primarily coronary heart disease (IHD) and its complications, are one of the main health problems in economically developed countries, causing high morbidity, disability and mortality among patients. According to WHO, its frequency ranges from 12–50%. Currently, the specialized literature actively discusses the problem of the progressive increase in the number of patients with coronary artery disease associated with the pathology of the gastroduodenal zone, and it is declared that such a combination often leads to their delayed diagnosis due to the atypical course. Рurpose of research. To study the specificity of the clinical features of ischemic heart disease in patients with erosive and ulcerative lesions of the gastroduodenal zone. Materials and methods. 146 patients with coronary artery disease were examined, among whom there were 12 (8,22%) patients with acute myocardial infarction (MI), 68 (46,57%) with progressive intense angina pectoris (PNS), tense angina pectoris (NS, functional class III–IV) – 66 (45,21%) people. The average age of the patients was 56,3 ± 2,4 years. Results and its discussion. The study of the clinical picture of ischemic heart disease in the observed patients demonstrates that the presence of such a comorbid background as ulcerative erosive lesions and the duodenum has certain differences. Examination of patients with coronary artery disease and HDF diseases revealed the following features. To identify the revealed features, the patients were divided into 3 groups: Patients with coronary artery disease and AMI (12 people); patients with ischemic heart disease, PNS FC4 (68 people); IHD, FC3 and FC4 (66 people). This distribution is ased on the severity of cardiac changes in the noted patients accompanied by gastroduodenal symptoms. Conclusions. Thus, in patients with coronary artery disease with a combination of HDP, there is a more severe, sometimes atypical course of ischemic heart disease, due to the presence of common etiopathogenetic factors of both pathologies.