The role of regulatory cytokines in formation and progressing of ischemic heart disease associated without assessment hyperericemia

The role of inflammatory factors in the formation, progression of ischemic heart disease (IHD) in the associated BSU and and atherosclerotic process as a whole has been studied in the article. The conducted studies showed that in patients with IHD (stable and unstable angina) associated BSU РОЛЬ РЕГУЛЯТОРНЫХ ЦИТОКИНОВ В ФОРМИРОВАНИИ И ПРОГРЕССИРОВАНИИ ИШЕМИЧЕСКОЙ БОЛЕЗНИ СЕРДЦА АССОЦИИРОВАННОЙ БЕССИМПТОМНОЙ ГИПЕРУРИКЕМИЕЙ 31 Journal of biomedicine and practice 1 (2018) there was an increase in the level of IL-6 in serum. As a result, a slight increase in the concentration of TNF-α and IL-6 serum in a group with a moderately elevated level of OXC was revealed. The results of correlation dependence and serum IL-6 show that in the control group, the TNF-α index is positively correlated with serum IL-6 (r = 0.29, P <0.05), while the level of IL-6 in the general group of patients with IHD associated asymptomatic GU was in more pronounced positive correlation with serum TNF-α (r = 0,37; P <0,02). The above important data on the participation of cytokines in the pathogenesis of immune disorders in coronary artery disease associated with asymptomatic GU will allow recommending a new approach in the future, both to diagnosis and to pathogenetically substantiated treatment of the disease, which hinders the development and progression of atherosclerotic process and endothelial dysfunction.