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THE STATE OF CARBOHYDRATE METABOLISM IN PATIENTS WITH HORMONE-ACTIVE PITUITARY ADENOMAS

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We examined 240 patients with hormonally active pituitary adenomas. In all patients, the level of fasting glycemia, glycated hemoglobin (HbA1c) was determined, and if necessary, an oral glucose tolerance test was performed. Assessment of the state of carbohydrate metabolism was carried out in accordance with the recommendations of ADA / EASD, 2019. A study of the state of carbohydrate metabolism revealed that the largest number of cases of diabetes was found among people with corticotropins - 45%, followed by patients with growth hormones - 18.33%, the smallest number of cases among patients with prolactinomas - 1.25%. It is important to note that in 23.3% with growth hormone and 20% with corticotropin, prediabetes was detected.

AUTHORS

A.Dosanova

R.Bazarbekova

Tags

# Акромегалия# Acromegaly# нарушения углеводного обмена# аденомы гипофиза# пролактинома# кортикотропинома# uglevod almashinuvining buzilish# gipofiz adenomalari# akromegaliya# prolaktinoma# kortikotropinoma# disorders of carbohydrate metabo# pituitary adenomas# prolactinoma# corticotropinoma

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References

1. Sharma S. T., Nieman L. K., Feelders R. A.. Comorbidities in Cushing’s disease // Pituitary. 2015; 18(2): 188–194.

2. Hannon A. M., Thompson C. J., Sherlock M. Diabetes in Patients with Acromegaly //Current Diabetes Reports. 2017. Vol. 17.. 2. P. 8

3. Sebko T.V., Hejdar L.A., Koneeva S.S. Giperprolaktinemiya // Medical Journal of the Russian Federation, Russian Journal. 2016; 22 (5)/ - C/ 250-260. DOI 10.18821/0869-2106-2016-22-5-250-259.

4. Boockenooghe T., Sisino G., Aurientis S., Chinetti-Gbaguidi G., Kerr-Conte J., Staels B. et al. Adipose tissue macrophages(ATM)of obese patients are releasing cucreased levels of prolactin during an infl ammatory challenge: A role for prolactin in diabesity? Biochim. Biophys. Acta. 2014; 1842(4): 584—93.

5. Baldelli R. et al. Glucose homeostasis in acromegaly: effects of long‐acting somatostatin analogues treatment //Clinical endocrinology. – 2003. – Vol. 59. – №. 4. – P. 492-499.

6. Dreval' A.V., Trigolosova I.V., Vinogradova A.V. Mekhanizmy narushenij uglevodnogo obmena pri akromegalii v zavisimosti ot lecheniya [The mechanisms of disorders of carbohydrate metabolism in acromegaly, depending on the treatment] // Problemy endokrinologii - №1.2015. - tom 61. - str.23-29.

7. Urbani C, Sardella C, Calevro A, et al. Effects of medical therapies for acromegaly on giucose metabolism. European journal of endocrinology/ European Federation of Endocrine Societies. 2013;169 (1):99-108.

8. Hannon A. M., Thompson C. J., Sherlock M. Diabetes in Patients with Acromegaly //Current Diabetes Reports. 2017. Vol. 17.. 2. P. 8.

9. Giustina A. et al. Use of pegvisomant in acromegaly. An Italian Society of Endocrinology guideline //Journal of endocrinological investigation. 2014. Vol. 37.. 10. P. 1017-1030.

10. Melmed S. et al. A consensus on the diagnosis and treatment of acromegaly complications //Pituitary. 2013. Vol. 16.. 3. P. 294-302.

11. Standards of Medical Care in Diabetes-2019. Diabetes Care 2019 Jan; 42(Supplement 1): S1-S2

12. Breitschaft A. et al. Management of hyperglycemia associated with pasireotide (SOM230): healthy volunteer study //Diabetes research and clinical practice. 2014. Vol. 103.. 3. P. 458-465

13. Mikityuk M.R., Hizhnyak O.O., Sulima T.N. Sravnitel'naya ocenka nekotoryh pokazatelej uglevodnogo obmena u bol'nyh s gormonal'noaktivnymi adenomami gipofiza [Comparative evaluation of some indicators of carbohydrate metabolism in patients with hormonal pituitary adenomas]// Saharnyj diabet. 2014;(1):70–74.

14. Trigolosova I.V. , Dreval' A.V. Epidemiologiya i patogenez narushenij uglevodnogo obmena pri akromegalii (obzor literatury) [Epidemiology and pathogenesis of disorders of carbohydrate metabolism in acromegaly]// Regulyarnye vypuski «RMZh» №8 ot 06.05.2015 str. 436.

15. Hizhnyak O. O., Gogitidze T. G. Osobennosti uglevodnogo obmena u bol'nyh s prolaktinomami na etapah supressivnoj terapii agonistami dofamina [Features of carbohydrate metabolism in patients with prolactinomas at the stages of suppressive therapy with dopamine agonists] // Problemi endokrinnoї patologiї № 3, 2015. - S. 67-75.