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THE IMPORTANCE OF IMMUNE INFLAMMATION IN THEDEVELOPMENT OF SENILE AORTIC STENOSIS

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Eurasian Journal of Academic Research

Eurasian Journal of Academic Research

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ARTICLE ANNOTATION

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Senil aorta stenozi (SAS)-aorta qopqog'ining torayishi bilan bog'liq bo'lgan yurak kasalligi bo'lib, odatda yoshga bog'liq va jiddiy yurak-qon tomir muammolarini keltirib chiqaradi . Senil aortal stenoz dunyo bo’ylab keng tarqalayotgan va yildan –yilga soni ortib borayotgan kasalliklardan biridir. Uning o’ziga xosligi, u ko’proq katta yoshdagi odamlarda uchraydi va uning asosiy simptomlari kam, ular yashirin ko’rinishda namoyon bo’ladi. Bundan tashqari, SAS ning patogenetik rivojlanishida immune yallig’lanish jarayonlarining roli muhimligi ilmiy –tadqiqotlar bilan tasdiqlangan. Yallig'lanish jarayonlari fibroz va qopqoq to'qimalarining kalsifikatsiyasiga olib kelishi mumkin, bu esa qopqoqning torayishiga olib keladi. Ko'pgina tadqiqotlar shuni ko'rsatadiki, SAS bilan og'rigan bemorlarda immunitet tizimi faolligi, yallig'lanish o'choqlari va hujayralar migratsiyasi o'zgargan. Ushbu yallig'lanish jarayonlari tana tuzilishining o'zgarishiga va uning funktsiyasining pasayishiga olib keladi. Shunday qilib, immun yallig'lanish SAS rivojlanishida muhim rol o'ynaydi va bu holatni yaxshilash yoki oldini olish uchun ilmiy tadqiqotlar va yangi yondashuvlar zarur

AUTHORS

G.No'monova

Andijon davlat tibbiyot instituti

I.Sobirjonov

Andijon davlat tibbiyot instituti

Tags

# Senil aortal stenoz-SAS# immun yallig’lanish# fibrozlanish# kalsi almashunuvining buzilish# suyaklanish jarayoni# osteopontin# Kalsitonin va tiroksin almashunu# interleykin 6 va 8# xushdan ketish

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https://eroi.uz/11.0201/A1224-0190

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References

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