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Mastopatiya – ayollarning eng keng tarqalgan kasalligi bo’lib, mammologiyadagi kasalliklar oqimining 90% ini tashkil etadi. Fibroz kistoz
mastopatiya etiologiyasi oxirigacha aniqlanmagan bo’lib, lekin ko’p o’rganilgan xavf omillariga endokrin buzilishlar, xususan insulinorezistentlik
va qalqonsimon bez kasalliklari kiradi.
Maqsad. FKM bemorlardagi insulinorezistentlik uchrashi va mastopatiyaning klinik kechishiga metformin tasirini o’rganish.
Tadqiqot manbasi va usullari. Tadqiqot manbasi sifatida Toshkent tibbiyot akademiyasi Urganch filiali bazasida fibroz kistoz mastopatiya tashxisi
asosida davolangan 71 ta fertil (18 - 49) yoshdagi ayollar olindi. Bemorlarning o’rtacha yoshi 34,2±0,4 yoshni tashkil etdi. Bemorlarda tana vazni
indeksi o’rtacha 31,4 ±2,54 kg/m2 ni, НOMA indeksi 3,2 ± 0,25 tashkil qildi.
Barcha ayollarda qalqonsimon bezi 7,5 mGts chastotali MINDRAY DC 60 (Yaponiya) ultratovush apparati yordamida sut bezi va qalqonsimon
bez ultratovush tekshiruvi (UTT) o’tkazildi.
Xulosa. Insulinorezistentlikning kamayishi va mastopatiya klinik kechishi orasida kuchli ishonchli bog’liqlik mavjud (р≤0,001).
Insulinorezistenlik bilan kechuvchi mastopatiyasi bor ayollarda metformin qabul qilish va UTT xulosasi BIRADS toifasining kamayishi orasida
ishonchli bog’liqlik mavjud (р≤0,05

  • Read count 197
  • Date of publication 15-03-2022
  • Main LanguageO'zbek
  • Pages36-39
Ўзбек

Mastopatiya – ayollarning eng keng tarqalgan kasalligi bo’lib, mammologiyadagi kasalliklar oqimining 90% ini tashkil etadi. Fibroz kistoz
mastopatiya etiologiyasi oxirigacha aniqlanmagan bo’lib, lekin ko’p o’rganilgan xavf omillariga endokrin buzilishlar, xususan insulinorezistentlik
va qalqonsimon bez kasalliklari kiradi.
Maqsad. FKM bemorlardagi insulinorezistentlik uchrashi va mastopatiyaning klinik kechishiga metformin tasirini o’rganish.
Tadqiqot manbasi va usullari. Tadqiqot manbasi sifatida Toshkent tibbiyot akademiyasi Urganch filiali bazasida fibroz kistoz mastopatiya tashxisi
asosida davolangan 71 ta fertil (18 - 49) yoshdagi ayollar olindi. Bemorlarning o’rtacha yoshi 34,2±0,4 yoshni tashkil etdi. Bemorlarda tana vazni
indeksi o’rtacha 31,4 ±2,54 kg/m2 ni, НOMA indeksi 3,2 ± 0,25 tashkil qildi.
Barcha ayollarda qalqonsimon bezi 7,5 mGts chastotali MINDRAY DC 60 (Yaponiya) ultratovush apparati yordamida sut bezi va qalqonsimon
bez ultratovush tekshiruvi (UTT) o’tkazildi.
Xulosa. Insulinorezistentlikning kamayishi va mastopatiya klinik kechishi orasida kuchli ishonchli bog’liqlik mavjud (р≤0,001).
Insulinorezistenlik bilan kechuvchi mastopatiyasi bor ayollarda metformin qabul qilish va UTT xulosasi BIRADS toifasining kamayishi orasida
ishonchli bog’liqlik mavjud (р≤0,05

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