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Yurak etishmovchiligini rag'batlantirishda past tiroid gormoni funktsiyasining roli va qalqonsimon gormonlarni almashtirishning mumkin bo'lgan foydalari keng ko'lamda ko'rib chiqilgan.Shu nuqtai nazardan, yurak etishmovchiligi yurakdagi qalqonsimon gormonlar tizimining pastga regulyatsiyasiga olib kelishi mumkin.Ishlamay qolgan yurakda yadroviy tiroid retseptori darajasining pasayishi kuzatiladi. Bundan tashqari, qalqonsimon bo'lmagan kasallik sindromida yurak etishmovchiligi bilan T4 va T3 zardobidagi darajalari kamayadi. Hayvon modellarida bosimning haddan tashqari balandligidan kelib chiqqan yurak gipertrofiyasida tiroid retseptori darajasining pasayishi sodir bo'lishini ko'rsatish mumkin. Yurak yetishmovchiligi qarigan aholimiz orasida tobora ortib borayotgan tibbiy muammodir

  • Read count 6
  • Date of publication 25-05-2024
  • Main LanguageO'zbek
  • Pages 14-19
Ўзбек

Yurak etishmovchiligini rag'batlantirishda past tiroid gormoni funktsiyasining roli va qalqonsimon gormonlarni almashtirishning mumkin bo'lgan foydalari keng ko'lamda ko'rib chiqilgan.Shu nuqtai nazardan, yurak etishmovchiligi yurakdagi qalqonsimon gormonlar tizimining pastga regulyatsiyasiga olib kelishi mumkin.Ishlamay qolgan yurakda yadroviy tiroid retseptori darajasining pasayishi kuzatiladi. Bundan tashqari, qalqonsimon bo'lmagan kasallik sindromida yurak etishmovchiligi bilan T4 va T3 zardobidagi darajalari kamayadi. Hayvon modellarida bosimning haddan tashqari balandligidan kelib chiqqan yurak gipertrofiyasida tiroid retseptori darajasining pasayishi sodir bo'lishini ko'rsatish mumkin. Yurak yetishmovchiligi qarigan aholimiz orasida tobora ortib borayotgan tibbiy muammodir

Ўзбек

The role of low thyroid hormone function in promoting heart failure and the potential benefits of thyroid hormone replacement have been extensively reviewed. In this context, heart failure can lead to a down-regulation of the thyroid hormone system in the heart. In a failing heart, there is a decrease in the level of the nuclear thyroid receptor. In addition, serum levels of T4 and T3 decrease with heart failure in the non-thyroid disease syndrome. In animal models, it has been shown that a decrease in thyroid receptor levels occurs in hypertrophy of the heart caused by excessive elevation of pressure. Heart failure is a growing medical problem among our aging population

№ Author name position Name of organisation
1 Kayimov . . assistent Qarshi davlat universiteti
2 Ganjiyeva . . talaba Qarshi davlat universiteti
№ Name of reference
1 1.Klein I, Ojamaa K. Qalqonsimon bez gormoni va yurak-qon tomir tizimi.N Engl J Med.2001;344(7): 501–509.2.Xalilov, Hikmatulla, et al. "TELEMEDITSINANING PROFILAKTIK DAVOLANISHDA AHAMIYATI."Евразийскийжурналакадемическихисследований4.4 Part 2 (2024): 66-70.3.Dilshodovich, Khalilov Hikmatulla, Kayimov Mirzohid Normurotovich, andEsanov Alisher Akromovich. "RELATIONSHIP BETWEEN THYROID DISEASE AND TYPE 2 DIABETES." (2023).4.Ladenson PW. Qalqonsimon bez disfunktsiyasi bilan bog'liq yurak-qon tomir kasalliklarini aniqlash va boshqarish.Men J Med.1990;88(6): 638–641.5.Patil VC, Patil HV, Agrawal V, Patil S. Birlamchi hipotiroidizm bilan og'rigan bemorda yurak tamponadasi.Hind J Endokrinol Metab.2011;15(2-qo'shimcha): S144–S146.6.Xalilov, X. D., N. K. SHadmanova, and M. N. Qayumov. "Gipertireorizmni exsperemental modellashtirish." (2023).7.Miller AJ. 9-bo'lim: Yurakning limfa drenaji. In: Jonson, muharrir.Limfa qon aylanishining eksperimental biologiyasi.Elsevier Science Publishers, BV;8.Xalilov, H., Namiddinov, A., Sayfullayeva, D., & Hikmatova, G. (2024). TELEMEDITSINANING PROFILAKTIK DAVOLANISHDA AHAMIYATI.Евразийскийжурналакадемическихисследований,4(4 Part 2), 66-70.9.Aleksandr J.S. Xolesterin mavjudligi sababli "Oltin bo'yoq" ko'rinishidagi perikardial efüzyon.Brit Med J.;2:463.10.Dilshodovich, K. H., Normurotovich, K.M., & Akromovich, E. A. (2023). RELATIONSHIP BETWEEN THYROID DISEASE AND TYPE 2 DIABETES.11.Xalilov, X. D., SHadmanova, N. K., & Qayumov, M. N. (2023). Gipertireorizmni exsperemental modellashtirish.12.Turhan S, Tulunay C, Ozduman CM va boshqalar. Subklinik hipotiroidizmi bo'lgan bemorlarda tiroksin terapiyasining o'ng qorincha sistolik va diastolik funktsiyasiga ta'siri:1.Klein I, Ojamaa K. Qalqonsimon bez gormoni va yurak-qon tomir tizimi.N Engl J Med.2001;344(7): 501–509.2.Xalilov, Hikmatulla, et al. "TELEMEDITSINANING PROFILAKTIK DAVOLANISHDA AHAMIYATI."Евразийскийжурналакадемическихисследований4.4 Part 2 (2024): 66-70.3.Dilshodovich, Khalilov Hikmatulla, Kayimov Mirzohid Normurotovich, andEsanov Alisher Akromovich. "RELATIONSHIP BETWEEN THYROID DISEASE AND TYPE 2 DIABETES." (2023).4.Ladenson PW. Qalqonsimon bez disfunktsiyasi bilan bog'liq yurak-qon tomir kasalliklarini aniqlash va boshqarish.Men J Med.1990;88(6): 638–641.5.Patil VC, Patil HV, Agrawal V, Patil S. Birlamchi hipotiroidizm bilan og'rigan bemorda yurak tamponadasi.Hind J Endokrinol Metab.2011;15(2-qo'shimcha): S144–S146.6.Xalilov, X. D., N. K. SHadmanova, and M. N. Qayumov. "Gipertireorizmni exsperemental modellashtirish." (2023).7.Miller AJ. 9-bo'lim: Yurakning limfa drenaji. In: Jonson, muharrir.Limfa qon aylanishining eksperimental biologiyasi.Elsevier Science Publishers, BV;8.Xalilov, H., Namiddinov, A., Sayfullayeva, D., & Hikmatova, G. (2024). TELEMEDITSINANING PROFILAKTIK DAVOLANISHDA AHAMIYATI.Евразийскийжурналакадемическихисследований,4(4 Part 2), 66-70.9.Aleksandr J.S. Xolesterin mavjudligi sababli "Oltin bo'yoq" ko'rinishidagi perikardial efüzyon.Brit Med J.;2:463.10.Dilshodovich, K. H., Normurotovich, K.M., & Akromovich, E. A. (2023). RELATIONSHIP BETWEEN THYROID DISEASE AND TYPE 2 DIABETES.11.Xalilov, X. D., SHadmanova, N. K., & Qayumov, M. N. (2023). Gipertireorizmni exsperemental modellashtirish.12.Turhan S, Tulunay C, Ozduman CM va boshqalar. Subklinik hipotiroidizmi bo'lgan bemorlarda tiroksin terapiyasining o'ng qorincha sistolik va diastolik funktsiyasiga ta'siri:
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