Ҳаммаси бўлиб, 12 нафар аёллар вақтидан олдин туққан, бу эса 14,12% ни ташкил этди. Улардан 8 нафарида цервикал канал секрециясида плацентар α1-микроглобулин миқдори аниқланди, айни пайтда фақат 5 нафар аёлларда УТТ цервикометрия натижасига кўра ≤20 мм ни ташкил этди. Вақтидан олдин туққан 4 нафар аёлларда (48 соатдан 7 сутка давомида) нотўғри салбий натижани кўрсатди. 7 (8,2%) нафар аёлда плацентар α1-микроглобулин тест синамаси мусбат бўлди ва бу беморларда кескин туғруқ бошланди. Плацентар α1-микроглобулинни вақтидан олдин туғруқнинг сезгирлик синамаси 66,67% ни, спецификлик - 95,9%, УТТ цервикометрия спецификлиги - 47,9%, сезгирлик - 41,7% ни ташкил этди. Иккала усулни тандемда ишлатиш вақтидан олдин туғиш хавфини кескин тушириши мумкин. Цервикометрия натижасига кўра, бачадон буйни қисқа бўлган аёлларга цервикал каналда α1-микроглобулин миқдорини тест-синамасини ўтказиш тавсия этилади
Total of 12 patients had premature labour accounting for 14.12%. In 8 of them placental α1-microglobulin incervical secretion was positive and only in 5 patients cervical length was ≤20 mm according to ultrasound cervicometry.4 patients with premature birth (ranging from 48 hours to 7 days) had false-negative test results. 7 (8.2%) patients hada false-positive result of placental α1-microglobulin test, and these patients subsequently had term birth. The sensitivity of the test for placental α1-microglobulin as a marker of premature birth was 66.67%, specificity 95.9%, specificity ofultrasound cervicometry - 47.9%, and sensitivity - 41.7%. Use of the combination of both tests can significantlyreduce hyperdiagnosis of threatened preterm labour. Females with short cervix according to ultrasound cervicometry should reasonably be tested forplacental α1-microglobulin in cervical discharge; positive result of this test will be found in those whose probability togive preterm labour during the next 14 days reaches 72.72%, and high prognostic value of a negative test result allowsobserving the patients in outpatient setting
| № | Author name | position | Name of organisation |
|---|---|---|---|
| 1 | Shavazi N.N. |
| № | Name of reference |
|---|---|
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