In this study, the relationship between ADIPOQ gene 276 G>T polymorphism and type 2 diabetes in the population of Uzbekistan was studied. 276 G>T polymorphism in patients with T2DM, as a result of the analysis of frequency of occurrence of alleles, G allele was 62%, T allele - 38%. In conditionally healthy people, G and T alleles were found to be 56% and 44%, respectively. As a result of the study, there was no statistically significant correlation between the ADIPOQ gene 276 G>T polymorphism and the risk of developing type 2 diabetes (χ2=1.84; p=0.4). However, in the study of the 276 G>T polymorphism of the ADIPOQ gene, a high frequency of the alternative T allele was found in patients with type 2 diabetes and in the control group. Further studies with larger sample size are recommended to better study the effect of risk alleles on T2DM disease development.
| № | Имя автора | Должность | Наименование организации |
|---|---|---|---|
| 1 | Dalimova D. . | o'qituvchi | Ilg‘or texnologiyalar markazi |
| 2 | Reyimbergenova Z.A. | o'qituvchi | Ilg‘or texnologiyalar markazi |
| 3 | Ormonaliyeva S.U. | o'qituvchi | Ilg‘or texnologiyalar markazi |
| 4 | Abduvohidova Y.O. | o'qituvchi | Ilg‘or texnologiyalar markazi |
| 5 | Umarova S.M. | o'qituvchi | Ilg‘or texnologiyalar markazi |
| 6 | Abdunabiyev A.M. | o'qituvchi | Ilg‘or texnologiyalar markazi |
| 7 | Say E.A. | o'qituvchi | Ilg‘or texnologiyalar markazi |
| 8 | Soy V.E. | o'qituvchi | Ilg‘or texnologiyalar markazi |
| 9 | Ibragimova S.N. | o'qituvchi | Ilg‘or texnologiyalar markazi |
| 10 | Nurmatova S.B. | o'qituvchi | Ilg‘or texnologiyalar markazi |
| 11 | Sohibnazarova X.A. | o'qituvchi | Ilg‘or texnologiyalar markazi |
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