Рассмотрен вопрос о современных возможностях комплексной диагностики образования узлов щитовидной железы. Несмотря на многочисленные исследования, не всегда удается поставить точный морфологический диагноз узелков щитовидной железы, что свидетельствует о необходимости совершенствования существующих и поиска новых методов диагностики. В связи с этим весьма перспективными представляются сообщения об использовании измерения тканевого давления в щитовидной железе для дифференциальной диагностики различных патологий этого органа. В настоящее время ультразвуковое исследование является эффективным методом диагностики. В этой статье обсуждаются узлы щитовидной железы и их диагностика.
Рассмотрен вопрос о современных возможностях комплексной диагностики образования узлов щитовидной железы. Несмотря на многочисленные исследования, не всегда удается поставить точный морфологический диагноз узелков щитовидной железы, что свидетельствует о необходимости совершенствования существующих и поиска новых методов диагностики. В связи с этим весьма перспективными представляются сообщения об использовании измерения тканевого давления в щитовидной железе для дифференциальной диагностики различных патологий этого органа. В настоящее время ультразвуковое исследование является эффективным методом диагностики. В этой статье обсуждаются узлы щитовидной железы и их диагностика.
Qalqonsimon bez tuguni shakllanishini kompleks diagnostikasining zamonaviy imkoniyatlari masalasi ko'rib chiqilmoqda. Ko'p sonli tadqiqotlar o'tkazilishiga qaramay, qalqonsimon bez tugunlarining aniq morfologik diagnostikasini har doim ham to'g'ri yo'lga qo'yish mumkin emas, bu mavjud bo'lganlarni takomillashtirish va yangi diagnostik usullarni izlash zarurligini ko'rsatadi. Shu nuqtai nazardan, ushbu organning turli xil patologiyalarini differentsial diagnostika qilish uchun qalqonsimon bezlarda to'qima bosimini o'lchashni qo'llash bo'yicha hisobotlar juda istiqbolli ko'rinadi. Hozirda ultratovush tekshiruv usuli samarali diagnostik usul hisoblanadi. Ushbu maqolada qalqonsimon bez tugunlari va uning diagnostikasi muhokama qilinadi.
The question of modern possibilities of complex diagnostics of nodular formations of the thyroid gland is considered. Despite the large number of studies conducted, it is not always possible to correctly establish the exact morphological diagnosis of thyroid nodules, which indicates the need to improve existing and search for new more informative diagnostic methods. In this respect, reports on the use of tissue pressure measurements in the thyroid glands for differential diagnosis of various pathologies of this organ appear to be very promising. Currently, ultrasound is an effective diagnostic method. This article discusses thyroid nodules and its diagnosis.
| № | Muallifning F.I.Sh. | Lavozimi | Tashkilot nomi |
|---|---|---|---|
| 1 | Tyan A.A. | . | Андижанский Государственный медицинский институт |
| 2 | Rashidova S.U. | . | Андижанский Государственный медицинский институт |
| № | Havola nomi |
|---|---|
| 1 | 1. Moon WJ, Baek JH, Jung SL, Moon WJ, Baek JH, Jung SL, Kim DW, Kim EK, Kim JY, Kwak JY, et al: Ultrasonography and the ultrasound-based management of thyroid nodules: Consensus statement and recommendations. Korean J Radiol. 12:1–14. 2011. |
| 2 | 2. Wang Y and Wang W: Increasing incidence of thyroid cancer in Shanghai. China, 1983-2007. Asia Pac J Public Health. 27:NP223–NP229. 2015. |
| 3 | 3. Kitahara CM and Sosa JA: The changing incidence of thyroid cancer. Nat Rev Endocrinol. 12:646–653. 2016. |
| 4 | 4. Acar T, Ozbek SS and Acar S: Incidentally discovered thyroid nodules: Frequency in an adult population during Doppler ultrasonographic evaluation of cervical vessels. Endocrine. 45:73–78. 2014. |
| 5 | 5. Paschke R, Hegedüs L, Alexander E, Valcavi R, Papini E and Gharib H: Thyroid nodule guidelines: Agreement, disagreement and need for future research. Nat Rev Endocrinol. 7:354–361. 2011. |
| 6 | 6. Hoang JK, Riofrio A, Bashir MR, Kranz PG and Eastwood JD: High variability in radiologists' reporting practices for incidental thyroid nodules detected on CT and MRI. AJNR Am J Neuroradiol. 35:1190–1194. 2014. |
| 7 | 7. Lim HK, Park ST, Ha H and Choi SY: Thyroid nodules detected by contrast-enhanced magnetic resonance angiography: Prevalence and clinical significance. PLoS One. 11(e0149811)2016. |
| 8 | 8. Kim TH, Ji YB, Song CM, Kim JY, Choi YY, Park JS and Tae K: SUVmax of 18F-FDG PET/CT in the differential diagnosis of benign and malignant thyroid nodules according to tumor volume. World J Surg Oncol. 13(217)2015. |
| 9 | 9. Richmond B, Statler K, Judhan R, Mangano W and Thompson S: Sonographic appearance is useful in predicting the extent of initial operative therapy for thyroid nodules classified as ‘suspicious for malignancy’. Am Surg. 82:692–697. 2016. |
| 10 | 10. Palaniappan MK, Aiyappan SK and Ranga U: Role of gray scale, color Doppler and spectral Doppler in differentiation between malignant and benign thyroid nodules. J Clin Diagn Res. 10:TC01–TC06. 2016. |
| 11 | 11. Zhang Y, Luo YK, Tang J, Li M, Wang ZL and Wen Q: Clinical value of ultrasonography in diagnosing diffuse thyroid diseases accompanied with suspicious nodules. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 37:290–293. 2015. |
| 12 | 12. Chen HY, Liu WY, Zhu H, Jiang DW, Wang DH, Chen Y, Li W and Pan G: Diagnostic value of contrast-enhanced ultrasound in papillary thyroid microcarcinoma. Exp Ther Med. 11:1555–1562. 2016. |
| 13 | 13. He Y, Wang XY, Hu Q, Chen XX, Ling B and Wei HM: Value of Contrast-enhanced ultrasound and acoustic radiation force impulse imaging for the differential diagnosis of benign and malignant thyroid nodules. Front Pharmacol. 27(1363)2018. |
| 14 | 14. Zhan J and Ding H: Application of contrast-enhanced ultrasound for evaluation of thyroid nodules. Ultrasonography. 37:288–297. 2018. 15. Magri F, Chytiris S and Chiovato L: The |
| 15 | 15. Magri F, Chytiris S and Chiovato L: The role of elastography in thyroid ultrasonography. Curr Opin Endocrinol Diabetes Obes. 23:416–422. 2016. |
| 16 | 16. Cantisani V, D'Andrea V, Biancari F, Medvedyeva O, Di Segni M, Olive M, Patrizi G, Redler A, De Antoni EE, Masciangelo R, et al: Prospective evaluation of multiparametric ultrasound and quantitative elastosonography in the differential diagnosis of benign and malignant thyroid nodules: Preliminary experience. Eur J Radiol. 81:2678–2683. 2012. |
| 17 | 17. Zhang Y, Zhou P, Tian SM, Zhao YF, Li JL and Li L: Usefulness of combined use of contrast-enhanced ultrasound and TI-RADS classification for the differentiation of benign from malignant lesions of thyroid nodules. Eur Radiol. 4:1527–1536. 2017. |
| 18 | 18. Sui X, Liu HJ, Jia HL and Fang QM: Contrast-enhanced ultrasound and real-time elastography in the differential diagnosis of malignant and benign thyroid nodules. Exp Ther Med. 12:783–791. 2016. |
| 19 | 19. Wen Luo Yunfei Zhang Jiani Yuan Xiao Yang Lina Pang Lei Ding Peidi Zhang Liwen Liu Xiaodong Zhou. Differential diagnosis of thyroid nodules through a combination of multiple ultrasonography techniques: A decision-tree model. doi.org/10.3892/etm.2020.8621. |
| 20 | 20. Zhang YZ, Xu T, Gong HY, Li CY, Ye XH, Lin HJ, Shen MP, Yang DT and Wu XH: Application of high-resolution ultrasound, real-time elastography, and contrast-enhanced ultrasound in differentiating solid thyroid nodules. Medicine (Baltimore). 95(e5329)2016. |
| 21 | 21. Reginelli A, Urraro F, di Grezia G, Napolitano G, Maggialetti N, Cappabianca S, Brunese L and Squillaci E: Conventional ultrasound integrated with elastosonography and B-flow imaging in the diagnosis of thyroid nodular lesions. Int J Surg. 12 (Suppl 1):S117–S122. 2014. |
| 22 | 22. Zhao RN, Zhang B, Yang X, Jiang YX, Lai XJ and Zhang XY: Logistic regression analysis of contrast-enhanced ultrasound and conventional ultrasound characteristics of sub-centimeter thyroid nodules. Ultrasound Med Biol. 41:3102–3108. 2015. |
| 23 | 23. Argalia G, De Bernardis S, Mariani D, Abbattista T, Taccaliti A, Ricciardelli L, Faragona S, Gusella PM and Giuseppetti GM: Ultrasonographic contrast agent: Evaluation of time-intensity curves in the characterisation of solitary thyroid nodules. Radiol Med. 103:407–413. 2002. |
| 24 | 24. Zhang Y, Luo YK, Zhang MB, Li J, Li J and Tang J: Diagnostic accuracy of contrast-enhanced ultrasound enhancement patterns for thyroid nodules. Med Sci Monit. 22:4755–4764. 2016. |
| 25 | 25. Jiang J, Shang X, Zhang H, Ma W, Xu Y, Zhou Q, Gao Y, Yu S and Qi Y: Correlation between maximum intensity and microvessel density for differentiation of malignant from benign thyroid nodules on contrast-enhanced sonography. J Ultrasound Med. 33:1257–1263. 2014 |
| 26 | 26. Giusti M, Campomenosi C, Gay S, Massa B, Silvestri E, Monti E and Turtulici G: The use of semi-quantitative ultrasound elastosonography in combination with conventional ultrasonography and contrast-enhanced ultrasonography in the assessment of malignancy risk of thyroid nodules with indeterminate cytology. Thyroid Res. 7(9)2014. |
| 27 | 27. Xuehua Xi, Luying Ga, Qiong Wu, Shibao Fang Jingzhu Xu, Ruyu Liu, Xiao Yang, Shenling Zhu, Ruina Zhao, Xingjian Lai, Xiaoyan Zhang, Bo Zhang and Yuxin Jiang. Differentiation of Thyroid Nodules Difficult to Diagnose With Contrast-Enhanced Ultrasonography and Real-Time Elastography. doi.org/10.3389/fonc.2020.00112. |
| 28 | 28. Grant EG, Tessler FN, Hoang JK, Langer JE, Beland MD, Berland LL, et al. Thyroid ultrasound reporting lexicon: white paper of the ACR thyroid imaging, reporting and data system (TIRADS) committee. J Am Coll Radiol. (2015) 12:1272–9. doi: 10.1016/j.jacr.2015.07.011. |
| 29 | 29. Frates MC, Benson CB, Doubilet PM, Cibas ES, Marqusee E. Can color doppler sonography aid in the prediction of malignancy of thyroid nodules? J Ultrasound Med. (2003) 22:127–31. doi: 10.7863/jum.2003.22.2.127. |
| 30 | 30. Asteria C, Giovanardi A, Pizzocaro A, Cozzaglio L, Morabito A, Somalvico F, et al. US- elastography in the differential diagnosis of benign and malignant thyroid nodules. Thyroid. (2008) 18:523–31. doi: 10.1089/thy.2007.0323. |
| 31 | 31. Hegedus L. Clinical practice. The thyroid nodule. N Engl J Med. 2004;351(17):1764–71. |
| 32 | 32. Tan GH, Gharib H. Thyroid incidentalomas: management approaches to nonpalpable nodules discovered incidentally on thyroid imaging. Ann Intern Med. 1997;126(3):226–31. |
| 33 | 33. Gharib H, Papini E. Thyroid nodules: clinical importance, assessment, and treatment. Endocrinol Metab Clin North Am. 2007;36(3):707–35. vi. |
| 34 | 34. Haugen BR, Alexander EK, Bible KC, et al. 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid. 2016;26(1):1–133. |
| 35 | 35. Leenhardt L, Hejblum G, Franc B, et al. Indications and limits of ultrasound-guided cytology in the management of nonpalpable thyroid nodules. J Clin Endocrinol Metab. 1999;84(1):24–8. |
| 36 | 36. Papini E, Guglielmi R, Bianchini A, et al. Risk of malignancy in nonpalpable thyroid nodules: predictive value of ultrasound and color-Doppler features. J Clin Endocrinol Metab. 2002;87(5):1941–6. |
| 37 | 37. Nam-Goong IS, Kim HY, Gong G, et al. Ultrasonography-guided fine-needle aspiration of thyroid incidentaloma: correlation with pathological findings. Clin Endocrinol (Oxf). 2004;60(1):21–8. |
| 38 | 38. Cappelli C, Castellano M, Pirola I, et al. The predictive value of ultrasound findings in the management of thyroid nodules. QJM. 2007;100(1):29–35. |
| 39 | 39. Frates MC, Benson CB, Doubilet PM, et al. Prevalence and distribution of carcinoma in patients with solitary and multiple thyroid nodules on sonography. J Clin Endocrinol Metab. 2006;91(9):3411–7. |
| 40 | 40. Moon WJ, Jung SL, Lee JH, et al. Benign and malignant thyroid nodules: US differentiation--multicenter retrospective study. Radiology. 2008;247(3):762–70. |
| 41 | 41. Remonti LR, Kramer CK, Leitao CB, Pinto LC, Gross JL. Thyroid ultrasound features and risk of carcinoma: a systematic review and meta-analysis of observational studies. Thyroid. 2015;25(5):538–50. |
| 42 | 42. Brito JP, Gionfriddo MR, Al Nofal A, et al. The accuracy of thyroid nodule ultrasound to predict thyroid cancer: systematic review and meta-analysis. J Clin Endocrinol Metab. 2014;99(4):1253–63. |
| 43 | 43. Bonavita JA, Mayo J, Babb J, et al. Pattern recognition of benign nodules at ultrasound of the thyroid: which nodules can be left alone? AJR Am J Roentgenol. 2009;193(1):207–13. |
| 44 | 44. Moon WJ, Kwag HJ, Na DG. Are there any specific ultrasound findings of nodular hyperplasia (“leave me alone” lesion) to differentiate it from follicular adenoma? Acta Radiol. 2009;50(4):383–8. |
| 45 | 45. URAZBAEV I. et al. DEVELOPMENT OF AGROTECHNICAL METHODS AND APPLICATION OF BIOMELIORANT PLANTS IN THE LOWER AREAS OF AMUDARYA //Journal of Critical Reviews. – 2020. – Т. 7. – №. 11. – С. 1327-1331. |
| 46 | 46. Niyazova Z., Khegay L., Rakhmanov A. EVALUATION OF AN IRRITATING AND ALLERGIZING ACTION OF A BIOPELLICLE FOR THE TREATMENT OF PENETRATING EYE INJURIES //Journal of Critical Reviews. – 2020. – Т. 7. – №. 11. – С. 1321-1326. |
| 47 | 47. Салахиддинов К. З. и др. Раневые покрытия–как эффективный метод лечения ожоговых ран. |
| 48 | 48. Zebiniso N. et al. FEATURES OF PSYCHOLOGICAL REHABILITATION IN PATIENTS WITH EYE INJURIES. |
| 49 | 49. Сыдиков А. А. и др. РЕЗУЛЬТАТЫ ПАТОМОРФОЛОГИЧЕСКОЙ ОЦЕНКИ ЭФФЕКТИВНОСТИ ПРИМЕНЕНИЯ ПЛЁНОЧНОГО БИОПОКРЫТИЯ «NOVACEL ZIYO» В ТЕРАПИИ ПРОНИКАЮЩИХ РАНЕНИЙ ГЛАЗ //Re-health journal. – 2020. – №. 3-2 (7). |