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The immune status has been studied at 35 HIV-infected of children with ARS. The control group of comparison consisted from 14 practically healthy faces. At a HIV-infected of patients with ARS has revealed deep infringements of the immune status, especially from the T-link of immunity and its subpopulations, and also frustration humoral an immunity link, suppression of proinflammatory cytokine IL-10 and increase proinflammatory IFN-γ. Under the influence of the spent treatment have not revealed certain changes from the immune status at patients. It is possible to ascertain only positive changes of maintenance IL-10 and parallel decrease IFN-γ in dynamics of treatment. In the main group there were 25 HIV-infected patients with ARS, and in the control group there were 14 practically healthy children of the same age who did not have a history of ARS and HIV. All 35 HIV-infected children were registered with the Bukhara Regional AIDS Center. Patients received antiretroviral therapy, antibacterial, anti-inflammatory and local therapy in a hospital setting.

  • O'qishlar soni 278
  • Nashr sanasi 30-07-2022
  • Asosiy tilIngliz
  • Sahifalar40-45
English

The immune status has been studied at 35 HIV-infected of children with ARS. The control group of comparison consisted from 14 practically healthy faces. At a HIV-infected of patients with ARS has revealed deep infringements of the immune status, especially from the T-link of immunity and its subpopulations, and also frustration humoral an immunity link, suppression of proinflammatory cytokine IL-10 and increase proinflammatory IFN-γ. Under the influence of the spent treatment have not revealed certain changes from the immune status at patients. It is possible to ascertain only positive changes of maintenance IL-10 and parallel decrease IFN-γ in dynamics of treatment. In the main group there were 25 HIV-infected patients with ARS, and in the control group there were 14 practically healthy children of the same age who did not have a history of ARS and HIV. All 35 HIV-infected children were registered with the Bukhara Regional AIDS Center. Patients received antiretroviral therapy, antibacterial, anti-inflammatory and local therapy in a hospital setting.

Muallifning F.I.Sh. Lavozimi Tashkilot nomi
1 Narzullaev N.U. Doctor of medical sciences, associate professor Bukhara State Medical Institute
Havola nomi
1 1. Ikramova F.S., Radjabov R.R. Improving tactics of treatment of allergic rhinitis with chronic diffus diseases// Eurasian journal of academic research Volume 1, Issue 1 April 2021. – P. 760-767. 2. Ikramova F.S., Erkinov N.N. Evaluation of the effect of hygienic isotonic nose in pregnant women on early active rhinometry indicators //Eurasian journal of academic research Volume 1, Issue 1 April 2021. –P. 668-673. 3. Nurov U.I., Ikramova F.S. Features Of Non-Specific Protection Factors And Cytokine Status In Inflammatory Diseases Of The Paranasal Sinuses In Twin Children// The american journal of medical sciences and pharmaceutical research Volume 3 Issue 02, 2021. –P. 2689-1026 4. Nurov U.I., Ikramova F.S., Alimova Sh.A. Functional status of immune status in inflammatory diseases of the paranasal sinuses in twin children// Academic research in educational sciences volume 2 | issue 5 | 2021 ISSN: 2181-1385 Scientific Journal Impact Factor (SJIF) 2021: 5.723, pp 238-246. 5.Narzullaev .N.U. The characteristic of the immune status at hiv- infected children with acute rhinosinusitis . International scientific and practical conference.ADTI.2019.pp.223-231. 6.Narzullaev .N.U. Fregvency of occurrence of the exudative average otitis at the HIV-infected children. International scientific and practical conference.ADTI.2019. pp.232-240 7. Narzullaev N.U. Clinic-immunological features the current of the chronic tonsillitis at a HIV-infected children depending on infection ways. //International scientific review of the problems and prospects of modern science and aducation. Boston.USA. 2018. P.- 50-52. 8. Narzullaev N.U. FarGALS efficiency in complex treatment of HIV-infected children with acute purulent sinusitis//European Science Review. - Austria, 2017. - No.1-2. -Р.86-88. 9 . Narzullaev N.U. The Incidence of exudative otitis media in HIV-infected children//International Journal BIOMEDICINE (IJBM) USA. – 2019. -No.1. -Р.211-213. 10. Narzullaev N.U. Immune Status of HIV-positive Children with Acute Rhinosinusitis//International Journal of Public Health Science (IJPHS) USA. – 2019. - Vol. 2, No.3. – Р.. 83-88.
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