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ANTIEPILEPTIC PHARMACOTHERAPY IS A LEADING FACTOR IN THE INDUCED PATHOMORPHOSIS OF EPILEPSY

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MAQOLA ANNOTATSIYASI

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Only 47 (52%) patients with MG, 21 (57%) with M and 26 (48%) with F were prescribed therapy at the onset of the disease, and it was rationally selected only in 41 (45%) cases –in 19 (51%) with M and 22 (41%) with F (p> 0.05). Of the 82 (100%) patients receiving therapy at the time of examination, 37 (45%) were taking basic, 20 (24%) modern, 24 (29%) a combination of basic and modern AEDs and in about 2% of cases a combination with the use of 1st generation drugs. Monotherapy was carried out in 45 (55%), polytherapy –in 37 (45%) of them. Of the 19 (100%) patients taking CBZ as starting monotherapy, 10 (52%) took the drug in a non-prolonged form, twice a day

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# epilepsy# pathomorphosis# antiepileptic pharmacotherapy

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Foydalanilgan adabiyotlar

1.Avakyan G. N., Blinov D. V., Lebedeva A. V., Burd S. G., AvakyanG. G. Classification of epilepsy of the International League Against Epilepsy: revision and update of 2017. Epilepsy and paroxysmal conditions. 2017; 9 (1): 6-25. DOI: 10.17749/2077-8333.2017.9.1.006-025.2.Rudakova I. G. Starter therapy of epilepsy in adults. Strategy and tactics. RMJ. 2014; 22 (16): 1147-1150.3.Maryenko L. B. Therapeutic pathomorphosis of epilepsy in light of the results of treatment with drugs of different generations. Journal of Neurology and Psychiatry named after S. S. Korsakov. Specialissue. 2014; 114 (4): 18-22.4.Kalinin V. A. Modeling the pathogenesis of epilepsy in different age groups based on the results of visual evoked potentials of the brain to a reversed chessboard pattern. Problems of Telecommunication Engineering and Technology. Proceedings of the XIV International Scientific and Technical Conference. Samara. 2013; 562-565.5.Tovaralieva G. F. Epilepsy and approaches to its treatment. In the collection: Intellectual Potential of the XXI Century. Proceedings of the International (correspondence) Scientific and Practical Conference. Scientific (non-periodical) electronic publication. Under the general editorship of A. I. Vostretsov. 2016; 175-182.

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