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STUDYING OF BASIDIAL MUSHROOMS OF POLYSACCHARIDE COMPOSITION GROWING IN UZBEKISTAN

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Ўзбекистон кимё журнали

Ўзбекистон кимё журнали

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Background. Polysaccharides isolated from basidiomycetes possess immunomodulatory, antiviral, hepatoprotective, antiproliferative, hypolipidemic, adaptogenic activities, and therefore are practically significant. These polysaccharides differ in their structure, physicochemical properties, monosaccharide composition, type of glycosidic linkage, molecular weight and water- or alkali-soluble properties. In addition, their biological activity depends on molecular parameters and structure. In this regard, the study of these parameters of polysaccharides isolated from basidiomycetes is relevant. Purpose. Isolation of polysaccharides from basidiomycetes distributed in the Republic of Uzbekistan and study of their composition using physicochemical methods. Methodology. Polysaccharides were isolated by aqueous, alkaline, and acidic fractionation methods. Polysaccharide samples isolated were studied using IR and UV spectroscopy methods. The monosaccharide composition of the polysaccharides was determined by paper chromatography, the molecular mass characteristics were determined by gel chromatography. The total sugar content of the polysaccharides was evaluated by the phenol-sulfuric acid method. Originality. In this report, polysaccharides were isolated for the first time from some basidiomycetes distributed in the Republic, and monosaccharide composition along with molecular parameters were studied by physicochemical methods. Findings. Under laboratory conditions, polysaccharides were extracted from fungi using aqueous, alkaline and acidic extraction, and their yields were determined. The overall structure, the monosaccharide composition, the average molecular weight (Mw), the total amount of sugar were evaluated. The polysaccharides isolated from fungi were found to be in a form melanin-glucan complex. Highlights: * polysaccharides were isolated from basidiomycete fungi; * the physicochemical properties of polysaccharides were studied.

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# хроматография# chromatography# polysaccharide# полисахарид# absorption# моносахаридный состав# фракция# fraction# базидиал замбуруғлар# моносахарид таркиб# ютилиш спектри# углевод миқдори.# базидиальные грибы# спектр поглощения# количество углеводов.# basidiomycetes# monosaccharide composition# sugar content.

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https://eroi.uz/11.0030/A1219-0016

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