Янги ишлаб чиқарилган кукун шаклидаги Гепроцел гемостатик воситасининг экспериментал текширувлари 198±2,7г. вазнли 60 та оқ зотсиз каламушларда ўтказилди. Морфологик ўзгаришлар операциядан кейинги 3, 12 соат, хамда 1, 3, 7, 14 ва 30 кундан сўнг текшириб кўрилди. Бунда уларнинг макроскопик ва микроскопик ўзгариш жихатлари ўрганилди. Ўтказилган текширув натижалари Гепроцел гемостатик воситаси паренхиматоз қон кетишини самарали тўхтатишини кўрсатди. Микроскопик кузатувлар жигар юзасидаги жарохатнинг юпқа бириктирувчи тўқимали чандиқ хосил бўлиши билан аста-секин бтишини кўрсатди. Гепроцел гемостатик кукунига, организм учун ёт модда сифатида, эрта муддатларда енгил морфологик жараён кўринишида яллиғланиш хосил бўлиб, имплантат сўрилиши даврида тезда камайиб боради. Назорат гуруҳида эса худди шу давр мобайнида яллиғланиш жараёнининг кучайиб бориши кузатилди. Гепроцел кукуни организмда қўлланилганда 14–21 кун ичида тўлиқ сўрилиб кетиши кузатилди. Шундай қилиб, кукун шаклидаги янги Гепроцел қон тўхтатувчи воситаси паренхиматоз қон кетишини тўхтатувчи сифатида жароҳат ва операциядан кейин қўлланилиши мумкин.
Experimental study of new polycomposition haemostatic powder was performed. 60 white male rabbits with weight 198 + 2,7 g were used. Morphologic alterations were studied at 3, 12 hours, 1, 3, 7, 14, 30 days after the operation. Results revealed the haemostatic effect of Heprocel powder. Microscopic data showed the gradual healing of the liver wound forming the thin connective tissue in injured zone. The slight inflammation developed as foreign body reaction, which reduced with implant biodegradation. Inflammation signs were manifested in the control group. The complete biodegradation of haemostatic powder Heprocel was registered on 14 – 21 days. Thus, the new haemostatic agent Heprocel might be used for parenchymal bleeding control in trauma and operation.
| № | Muallifning F.I.Sh. | Lavozimi | Tashkilot nomi |
|---|---|---|---|
| 1 | Alimov M.M. |
| № | Havola nomi |
|---|---|
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