ОСОБЕННОСТИ ПАТОМОРФОЛОГИИ ПОСЛЕДА ПРИ НЕДОНАШИВАНИИ БЕРЕМЕННОСТИ ИНФЕКЦИОННОГО ГЕНЕЗА

Muddatidan  oldin  tug’ruq  homiladorlikning  eng  keng  tarqalgan 
asoratidir  va  uning  chastotasi  barcha  klinik  homiladorliklarning  10-20%i  
hisoblanadi.    Barcha  homiladorlik  holatlarining  5-20%  ni  homilaning  nobud 
bo’lishi, 5 10% ni erta tug’ruq tashkil qiladi.  Odatiy muddatidan oldingi tug’ruq sabablari  ko'pfaktorli  hisoblanadi  va  ko'plab  tadqiqotchilar  infektsiyani  etakchi 
omillardan  biri    deb  hisoblashadi.  Ushbu  maqolada  platsenta  to'qimalarida 
patomorfologik  o'zgarishlarga  va  erta  tug'ilishga  olib  keladigan  infektsiyalarning 
etologik  roli  keltirilgan.  Endometriumdagi  infektsi  ona  gentlarning  birgalikda 
endokrinopatiyalarning  rivojlanishiga,  mahalliy  va  umumiy  immune 
mexanizmlarning  muvozanatiga,  platsentatsiya  jarayonlarini  buzishga, 
embrionning  shakllanishiga  va  homiladorlikni  tugatish  uchun  qo'shimcha 
sharoitlarni yaratishga yordam beradi. 

Miscarriage is the most common complication of pregnancy and 
its frequency is 10-20 % of all clinically established pregnancies. Interruption in 
the early stages is from 5 to 20 % of all pregnancies , premature birth -5-10 %. The 
causes  of  habitual  miscarriage  are  multifactorial,  and  one  of  the  leading  factors 
many researchers consider infection. This article presents the role of ethological 
infections  leading  to  pathological  changes  in  the  tissues  of  the  placenta  and 
premature  birth.  The  persistence  of  infectious  agents  in  the  endometrium 
contributes to the progression of concomitant endocrinopathies, imbalance of local 
and  General  immune  mechanisms,  leading  to  disruption  of  the  processes  of 
placentation,  embryo  formation  and  the  creation  of  additional  conditions  for 
abortion.