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Ushbu tadqiqot xromatografik va spektroskopik usullardan foydalangan holda biologik faol ikkilamchi metabolitlarni ajratib olish va tavsiflash uchun olib borildi. Ephedra equisetina Bunge oʻsimligi Oʻzbekiston Respublikasining Fargʻona viloyatida yigʻib olingan. Turlarning mansubligi gerbariy namunasi bilan solishtirish orqali aniqlandi. O‘simlik tarkibiy qismlarini ajratish uchun Ephedra equisetina etil spirti bilan ekstraksiya qilindi. Efedrin alkaloidi birinchi marta oʻzbek florasi populyatsiyasiga tegishli Ephedra equisetina Bunge yer ustki qismining spirtli ekstraktidan xromatografiya usullari yordamida ajratib olingan. Alkaloidning tuzilishi IQ, 1H va 13C NMR, shuningdek, HSQC, HMBC spektroskopiyasi yordamida o‘rnatildi. O‘zbekiston Respublikasi Farg‘ona viloyatida o‘sadigan Ephedra equisetina Bunge o‘simligining alkaloid tarkibi birinchi marta o‘rganildi.

  • Internet havola
  • DOIhttps://doi.org/10.56292/SJFSU/vol28_iss3/a49
  • UzSCI tizimida yaratilgan sana 04-10-2022
  • O'qishlar soni 350
  • Nashr sanasi 23-09-2022
  • Asosiy tilO'zbek
  • Sahifalar257-261
Ўзбек

Ushbu tadqiqot xromatografik va spektroskopik usullardan foydalangan holda biologik faol ikkilamchi metabolitlarni ajratib olish va tavsiflash uchun olib borildi. Ephedra equisetina Bunge oʻsimligi Oʻzbekiston Respublikasining Fargʻona viloyatida yigʻib olingan. Turlarning mansubligi gerbariy namunasi bilan solishtirish orqali aniqlandi. O‘simlik tarkibiy qismlarini ajratish uchun Ephedra equisetina etil spirti bilan ekstraksiya qilindi. Efedrin alkaloidi birinchi marta oʻzbek florasi populyatsiyasiga tegishli Ephedra equisetina Bunge yer ustki qismining spirtli ekstraktidan xromatografiya usullari yordamida ajratib olingan. Alkaloidning tuzilishi IQ, 1H va 13C NMR, shuningdek, HSQC, HMBC spektroskopiyasi yordamida o‘rnatildi. O‘zbekiston Respublikasi Farg‘ona viloyatida o‘sadigan Ephedra equisetina Bunge o‘simligining alkaloid tarkibi birinchi marta o‘rganildi.

Русский

Настоящее исследование было проведено для выделения и характеристики биологически активных вторичных метаболитов с использованием хроматографических и спектроскопических методов. Растение Ephedra equisetina Bunge было собрано в Ферганской области Республики Узбекистан. Видовая принадлежность определялась сопоставлением с гербарным образцом.   Для выделения компонентов растения Ephedra equisetina было экстрагировано этиловым спиртом. Методами хроматографии  из спиртового экстракта  надземной части Ephedra equisetina Bunge, из популяции Узбекской  флоры впервые выделен алкалоид эфедрин. Структура алкалоида была установлена с помощью ИК, ЯМР 1Н и 13С, а также HSQC, HMBC спектроскопии. Впервые изучен алкалоидный состав Ephedra equisetina Bunge произрастающей в Ферганской области Республики Узбекистан.

English

The present study was carried out to extract and characterize biologically active secondary metabolites using chromatographic and spectroscopic methods. The plant Ephedra equisetina Bunge was collected in Fergana region of the Republic of Uzbekistan. The species affiliation was determined by comparison with the herbarium specimen. To isolate the plant components, Ephedra equisetina was extracted with ethyl alcohol. Ephedrine alkaloid was isolated for the first time from an alcoholic extract of the aerial part of Ephedra equisetina Bunge, from the population of the Uzbek flora, using chromatography methods. The structure of the alkaloid was established using IR, 1H and 13C NMR, as well as HSQC, HMBC spectroscopy. For the first time, the alkaloid composition of Ephedra equisetina Bunge, which grows in the Fergana region of the Republic of Uzbekistan, has been studied.
 

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