Dynamics of blood morphological parameters in hypotrophic dogs treated with the immunomodulator Miopets®

This article studied the clinical and hematological efficacy of gamma-globulin and the immunomodulator Miopets® in puppies. Animals of the first experimental group were parenterally administered gamma-globulin at a dose of 1 ml per 1 kg of body weight together with the immunomodulator Miopets®, while animals of the control group received only gamma-globulin. At the beginning of the experiment, the animals showed gastrointestinal disorders, diarrhea, vomiting, weakness, pale mucous membranes, and dull coat. After 60 days of observation, the clinical condition improved in both groups, but more pronounced positive dynamics were observed in the first group. In particular, body weight increased by an average of 1600 g, which was 700 g higher than in the control group. Hematological studies showed an increase in the number of erythrocytes, hemoglobin, hematocrit, and platelets, indicating activation of hematopoiesis and regenerative processes. Leukocyte and ESR parameters remained within physiological norms, while a decrease in inflammatory processes was noted. The results confirm that the combined use of gamma-globulin with the immunomodulator Miopets® enhances the immunobiological stability of puppies, improves metabolism, and accelerates clinical recovery.